End-to-end design of wearable sensors
Wearable devices provide an alternative pathway to clinical diagnostics by exploiting
various physical, chemical and biological sensors to mine physiological (biophysical and/or …
various physical, chemical and biological sensors to mine physiological (biophysical and/or …
Opportunities and challenges in the diagnostic utility of dermal interstitial fluid
M Friedel, IAP Thompson, G Kasting, R Polsky… - Nature Biomedical …, 2023 - nature.com
The volume of interstitial fluid (ISF) in the human body is three times that of blood. Yet,
collecting diagnostically useful ISF is more challenging than collecting blood because the …
collecting diagnostically useful ISF is more challenging than collecting blood because the …
A wireless patch for the monitoring of C-reactive protein in sweat
The quantification of protein biomarkers in blood at picomolar-level sensitivity requires
labour-intensive incubation and washing steps. Sensing proteins in sweat, which would …
labour-intensive incubation and washing steps. Sensing proteins in sweat, which would …
Wearable microneedle-based electrochemical aptamer biosensing for precision dosing of drugs with narrow therapeutic windows
Therapeutic drug monitoring is essential for dosing pharmaceuticals with narrow therapeutic
windows. Nevertheless, standard methods are imprecise and involve invasive/resource …
windows. Nevertheless, standard methods are imprecise and involve invasive/resource …
Wearable electrochemical sensors for the monitoring and screening of drugs
Wearable electrochemical sensors capable of noninvasive monitoring of chemical markers
represent a rapidly emerging digital-health technology. Recent advances toward wearable …
represent a rapidly emerging digital-health technology. Recent advances toward wearable …
Wearable devices for the detection of COVID-19
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Model-informed precision dosing of beta-lactam antibiotics and ciprofloxacin in critically ill patients: a multicentre randomised clinical trial
TMJ Ewoldt, A Abdulla, WJR Rietdijk, AE Muller… - Intensive Care …, 2022 - Springer
Purpose Individualising drug dosing using model-informed precision dosing (MIPD) of beta-
lactam antibiotics and ciprofloxacin has been proposed as an alternative to standard dosing …
lactam antibiotics and ciprofloxacin has been proposed as an alternative to standard dosing …
An antibody-based molecular switch for continuous small-molecule biosensing
We present a generalizable approach for designing biosensors that can continuously detect
small-molecule biomarkers in real time and without sample preparation. This is achieved by …
small-molecule biomarkers in real time and without sample preparation. This is achieved by …
Flexible hybrid sensor systems with feedback functions
Skin‐like wearable sensors are regarded as key technologies toward home‐based
healthcare, human–machine interfaces, robotics, prostheses, and enhanced …
healthcare, human–machine interfaces, robotics, prostheses, and enhanced …
Optimizing antimicrobial use: challenges, advances and opportunities
An optimal antimicrobial dose provides enough drug to achieve a clinical response while
minimizing toxicity and development of drug resistance. There can be considerable …
minimizing toxicity and development of drug resistance. There can be considerable …