While 7% of the men are infertile, currently, a genetic etiology is identified in less than 25%
of those men, and 30% of the infertile men lack a definitive diagnosis, falling in the …

Highlights•Identifiable genetic abnormalities contribute to 15%–20% of the most severe
forms of male infertility, azoospermia.•Klinefelter syndrome, XXY, is the most common X …

Background: One of the most common structural balanced chromosome rearrangements is
pericentric inversion of chromosome 9; inv (9)(p11q12), which is consider to be the variant of …

Infertility is a worldwide problem affecting about 15% of couples trying to conceive.
Asthenozoospermia (AZS) is one of the major causes of male infertility, diagnosed by …

Chromosomal polymorphisms are structural variations in chromosomes that define the
genomic variance of a species. These alterations are recurrent in the general population …

Introduction Thousands of genes are implicated in spermatogenesis, testicular development
and endocrine regulation of testicular function. The genetic contribution to male infertility is …

Pericentric inversion of human chromosome 9 [inv (9)] is a relatively common cytogenetic
finding. It is largely considered a clinically insignificant variant of the normal human …

Abstract Infertility affects 8%–12% of couples worldwide with a male factor contributing to
nearly 50% of couples either as a primary or contributing cause. Several genetic factors that …

The importance of chromosomal abnormalities in etiology of premature ovarian failure (POF)
is well known but in many cases, POF still remains idiopathic. We investigated the frequency …

Chromosomal polymorphisms involve heterochromatic regions and occur in the general
population. However, previous studies have reported a higher incidence of these variants in …