Lumbar intervertebral disc herniation, as a leading cause of low back pain, productivity loss,
and disability, is a common musculoskeletal disorder that results in significant …

Scoliosis is a deformity of the spine that in severe cases requires surgical treatment. There is
still disagreement among clinicians as to what the aim of such treatment is as well as the …

Intervertebral disc (IVD) degeneration and herniation often necessitate surgical interventions
including a discectomy with or without a nucleotomy, which results in a loss of the normal …

Growing clinical evidence suggests a correlation between diabetes and more frequent and
severe intervertebral disc failure, partially attributed to accelerated advanced glycation end …

The angiopoietin-1 receptor (Tie2) marks specific nucleus pulposus (NP) progenitor cells,
shows a rapid decline during aging and intervertebral disc degeneration, and has thus …

A comprehensive understanding of multiscale and multiphasic intervertebral disc mechanics
is crucial for designing advanced tissue engineered structures aiming to recapitulate native …

Precise control of tissue water content is essential for ensuring accurate, repeatable, and
physiologically relevant measurements of tissue mechanics and biochemical composition …

This review delves into the emerging field of the gut microbiota–brain axis, emphasizing its
bidirectional communication and implications for neurological health, particularly in trauma …

Abstract Purpose of Review Spinal ligament is an important component of the spinal column
in mitigating biomechanical stress. Particularly the posterior ligamentous complex, which is …

Cell therapy strategies hold great promise for nucleus pulposus (NP) regeneration and
intervertebral disc degeneration (IVDD) treatment. However, their therapeutic efficiency is …