Chagas cardiomyopathy: an update of current clinical knowledge and management: a scientific statement from the American Heart Association
Background: Chagas disease, resulting from the protozoan Trypanosoma cruzi, is an
important cause of heart failure, stroke, arrhythmia, and sudden death. Traditionally …
important cause of heart failure, stroke, arrhythmia, and sudden death. Traditionally …
Trypanosoma cruzi genetic diversity: Something new for something known about Chagas disease manifestations, serodiagnosis and drug sensitivity
B Zingales - Acta tropica, 2018 - Elsevier
The genetic diversity of Trypanosoma cruzi, the protozoan agent of Chagas disease, is
widely recognized. At present, T. cruzi is partitioned into seven discrete typing units (DTUs) …
widely recognized. At present, T. cruzi is partitioned into seven discrete typing units (DTUs) …
Randomized trial of benznidazole for chronic Chagas' cardiomyopathy
CA Morillo, JA Marin-Neto, A Avezum… - … England Journal of …, 2015 - Mass Medical Soc
Background The role of trypanocidal therapy in patients with established Chagas'
cardiomyopathy is unproven. Methods We conducted a prospective, multicenter …
cardiomyopathy is unproven. Methods We conducted a prospective, multicenter …
Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need
The WHO recognizes human African trypanosomiasis, Chagas disease and the
leishmaniases as neglected tropical diseases. These diseases are caused by parasitic …
leishmaniases as neglected tropical diseases. These diseases are caused by parasitic …
Chagas disease
JA Pérez-Molina, I Molina - The Lancet, 2018 - thelancet.com
Chagas disease is an anthropozoonosis from the American continent that has spread from
its original boundaries through migration. It is caused by the protozoan Trypanosoma cruzi …
its original boundaries through migration. It is caused by the protozoan Trypanosoma cruzi …
Pathology and pathogenesis of Chagas heart disease
KM Bonney, DJ Luthringer, SA Kim… - Annual Review of …, 2019 - annualreviews.org
Chagas heart disease is an inflammatory cardiomyopathy that develops in approximately
one-third of people infected with the protozoan parasite Trypanosoma cruzi. One way T …
one-third of people infected with the protozoan parasite Trypanosoma cruzi. One way T …
Chagas disease drug discovery: toward a new era
E Chatelain - Journal of biomolecular screening, 2015 - journals.sagepub.com
American trypanosomiasis, or Chagas disease, is the result of infection by the Trypanosoma
cruzi parasite. Endemic in Latin America where it is the major cause of death from …
cruzi parasite. Endemic in Latin America where it is the major cause of death from …
Over Six Thousand Trypanosoma cruzi Strains Classified into Discrete Typing Units (DTUs): Attempt at an Inventory
SF Brenière, E Waleckx, C Barnabé - PLoS neglected tropical …, 2016 - journals.plos.org
Trypanosoma cruzi, the causative agent of Chagas disease, presents wide genetic diversity.
Currently, six discrete typing units (DTUs), named TcI to TcVI, and a seventh one called …
Currently, six discrete typing units (DTUs), named TcI to TcVI, and a seventh one called …
Discrete typing units of Trypanosoma cruzi: Geographical and biological distribution in the Americas
Chagas disease caused by Trypanosoma cruzi is a public health issue in Latin America.
This highly diverse parasite is divided into at least seven discrete typing units (DTUs) TcI …
This highly diverse parasite is divided into at least seven discrete typing units (DTUs) TcI …
Parasite zoonoses and wildlife: one health, spillover and human activity
RCA Thompson - International journal for parasitology, 2013 - Elsevier
This review examines parasite zoonoses and wildlife in the context of the One Health triad
that encompasses humans, domestic animals, wildlife and the changing ecosystems in …
that encompasses humans, domestic animals, wildlife and the changing ecosystems in …