Over the past two decades, proton magnetic resonance spectroscopy (proton MRS) of the
brain has made the transition from research tool to a clinically useful modality. In this review …

In this paper an overview of time-domain and frequency-domain quantitation methods is
given. Advantages and drawbacks of these two families of quantitation methods are …

Objectives: To evaluate in vivo brain metabolite differences in control subjects, individuals
with premanifest Huntington disease (pre-HD), and individuals with early HD using 1H …

Non-invasive in vivo detection of cortical neurotransmitter concentrations and their changes
in the presence of pain may help to better understand the biochemical principles of pain …

Purpose The inherently poor SNR of MRS measurements presents a significant hurdle to its
clinical application. Denoising by machine or deep learning (DL) was proposed as a …

This article presents background information related to methodology for estimating brain
metabolite concentration from magnetic resonance spectroscopy (MRS) and magnetic …

Background The relationships between scan duration, signal-to-noise ratio (SNR) and
sample size must be considered and understood to design optimal GABA-edited magnetic …

This study examined the concentrations of brain metabolites visible to in-vivo 1 H-Magnetic
Resonance Spectroscopy (1 H-MRS) at 1.5 T in a sample of 28 normal subjects …

Purpose This study evaluates the performance of 2 processing methods, that is, principal
component analysis‐based denoising and Wiener deconvolution, to enhance the quality of …

The accuracy and precision of measurements of metabolite concentrations from short echo‐
time spectra has previously been characterized at l. 5 T as a function of signal‐to‐noise ratio …