Obesity and the nutrition transition in Sub‐Saharan Africa

NP Steyn, ZJ Mchiza - Annals of the New York academy of …, 2014 - Wiley Online Library
This review illustrates the outcomes of the nutrition transition in Sub‐Saharan Africa (SSA)
and its association with overweight and obesity; the relationship with the double burden of …

Child health, developmental plasticity, and epigenetic programming

Z Hochberg, R Feil, M Constancia, M Fraga… - Endocrine …, 2011 - academic.oup.com
Plasticity in developmental programming has evolved in order to provide the best chances of
survival and reproductive success to the organism under changing environments …

Ten putative contributors to the obesity epidemic

EJ McAllister, NV Dhurandhar, SW Keith… - Critical reviews in …, 2009 - Taylor & Francis
The obesity epidemic is a global issue and shows no signs of abating, while the cause of
this epidemic remains unclear. Marketing practices of energy-dense foods and institutionally …

Compensation for a bad start: grow now, pay later?

NB Metcalfe, P Monaghan - Trends in ecology & evolution, 2001 - cell.com
Nutritional conditions during key periods of development, when the architecture and modus
operandi of the body become established, are of profound importance in determining the …

Transposable elements: targets for early nutritional effects on epigenetic gene regulation

RA Waterland, RL Jirtle - Molecular and cellular biology, 2003 - Am Soc Microbiol
Early nutrition affects adult metabolism in humans and other mammals, potentially via
persistent alterations in DNA methylation. With viable yellow agouti (A vy) mice, which …

Developmental plasticity and human health

P Bateson, D Barker, T Clutton-Brock, D Deb… - Nature, 2004 - nature.com
Many plants and animals are capable of developing in a variety of ways, forming
characteristics that are well adapted to the environments in which they are likely to live. In …

Birth weight and risk of type 2 diabetes: a systematic review

PH Whincup, SJ Kaye, CG Owen, R Huxley, DG Cook… - Jama, 2008 - jamanetwork.com
Context Low birth weight is implicated as a risk factor for type 2 diabetes. However, the
strength, consistency, independence, and shape of the association have not been …

The role of vitamin D in nervous system health and disease

GC DeLuca, SM Kimball, J Kolasinski… - Neuropathology and …, 2013 - Wiley Online Library
Vitamin D and its metabolites have pleomorphic roles in both nervous system health and
disease. Animal models have been paramount in contributing to our knowledge and …

Developmental origins of the metabolic syndrome: prediction, plasticity, and programming

IC McMillen, JS Robinson - Physiological reviews, 2005 - journals.physiology.org
The “fetal” or “early” origins of adult disease hypothesis was originally put forward by David
Barker and colleagues and stated that environmental factors, particularly nutrition, act in …

ATF4-dependent transcription mediates signaling of amino acid limitation

MS Kilberg, J Shan, N Su - Trends in Endocrinology & Metabolism, 2009 - cell.com
Mammals respond to dietary nutrient fluctuations; for example, deficiency of dietary protein
or an imbalance of essential amino acids activates an amino acid response (AAR) signal …