How we treat primary immune thrombocytopenia in adults

X Liu, Y Hou, M Hou - Journal of Hematology & Oncology, 2023 - Springer
Primary immune thrombocytopenia (ITP) is an immune-mediated bleeding disorder
characterized by decreased platelet counts and an increased risk of bleeding. Multiple …

Thrombosis in immune thrombocytopenia—current status and future perspectives

D Swan, A Newland, F Rodeghiero… - British journal of …, 2021 - Wiley Online Library
Immune thrombocytopenia (ITP) is an autoimmune disorder in which a combination of
defective platelet production and enhanced clearance leads to thrombocytopenia. The …

Assessment of thrombotic risk during long-term treatment of immune thrombocytopenia with fostamatinib

N Cooper, I Altomare, MR Thomas… - Therapeutic …, 2021 - journals.sagepub.com
Background: Patients with immune thrombocytopenia (ITP) are at risk of bleeding and,
paradoxically, thromboembolic events (TEEs), irrespective of thrombocytopenia. The risk of …

[PDF][PDF] 皮质激素耐药或依赖的成人免疫性血小板减少症的治疗

彭军 - 临床血液学杂志, 2024 - lcxyen.whuhzzs.com
免疫性血小板减少症(immunethrombocytopenia, ITP) 是一种常见的自身免疫性出血性疾病,
表现为外周血血小板计数减低. 针对ITP 的经典初始治疗方案仍为糖皮质激素 …

[HTML][HTML] Evaluation of the procoagulant state in chronic immune thrombocytopenia before and after eltrombopag treatment—a prospective cohort study

WEM van Dijk, GC Poolen, A Huisman… - Journal of Thrombosis …, 2023 - Elsevier
Background Thrombopoietin receptor agonists are frequently used in treating immune
thrombocytopenia (ITP) owing to high response rates and good tolerability. ITP is associated …

[HTML][HTML] Real-world use of fostamatinib in patients with immune thrombocytopenia and thrombotic risk

AR Mehta, A Kefela, C Toste, D Sweet - Acta haematologica, 2022 - karger.com
Patients with immune thrombocytopenia (ITP) are at increased risk for bleeding and are
paradoxically at increased risk for thrombosis. Many patients with ITP have underlying …

Coronavirus disease 2019 in patients with chronic immune thrombocytopenia on thrombopoietin receptor agonists: new perspectives and old challenges

N Pantic, N Suvajdzic-Vukovic, M Virijevic… - Blood Coagulation & …, 2022 - journals.lww.com
There are limited data on the impact of severe acute respiratory syndrome corona virus 2
infection in patients previously diagnosed with primary immune thrombocytopenia (ITP) on …

Immunomodulation with romiplostim as a second‐line strategy in primary immune thrombocytopenia: The iROM study

A Schifferli, A Rüfer, A Rovo… - British journal of …, 2023 - Wiley Online Library
Thrombopoietin receptor agonists (TPO‐RAs) stimulate platelet production, which might
restore immunological tolerance in primary immune thrombocytopenia (ITP). The iROM …

The immune thrombocytopenia paradox: Should we be concerned about thrombosis in ITP?

A Saldanha, MP Colella, PR Villaça, J Thachil… - Thrombosis Research, 2024 - Elsevier
Despite the predisposition to bleeding, patients with immune thrombocytopenia (ITP) may
also have an increased risk of arterial and venous thrombosis, which can contribute to …

Outcomes of switching to avatrombopag following treatment failure with eltrombopag in paediatric immune thrombocytopenia: a real‐world study in China

X Cheng, Z Wang, S Dong, J Ma, J Meng… - British Journal of …, 2023 - Wiley Online Library
Immune thrombocytopenia (ITP) is an autoimmune bleeding disorder characterized by
isolated thrombocytopenia and a haemorrhagic risk. Thrombopoietin receptor agonists (TPO …