The leishmaniases are diseases caused by pathogenic protozoan parasites of the genus
Leishmania. Infections are initiated when a sand fly vector inoculates Leishmania parasites …

Governed by parasite and host factors and immunoinflammatory responses, the clinical
spectrum of leishmaniasis encompasses subclinical (inapparent), localised (skin lesions) …

Cutaneous leishmaniasis (CL) is caused by different species of the genus Leishmania. Pro-
and anti-inflammatory cytokines play different roles in resistance/susceptibility and the …

Advances in the understanding of leishmaniasis progression indicate that cellular
interactions more complex than the Th1/Th2 paradigm define the course of infection. Th17 …

The leishmaniases are a group of diseases caused by protozoan parasites of the genus
Leishmania. Various Leishmania species can cause human infection, producing a spectrum …

Leishmaniasis is a parasitic disease caused by various species of Leishmania, a unicellular
kinetoplastid protozoan flagellate. It manifests mainly in 3 clinical forms; visceral …

Studies in the recent years have advanced the knowledge of how host and parasite factors
contribute to the pathogenesis of human tegumentary leishmaniasis. Polymorphism within …

Protozoa of the genus Leishmania cause a wide variety of pathologies ranging from self‐
healing skin lesions to visceral damage, depending on the parasite species. The outcome of …

The host immune response has a critical role not only in protection from human
leishmaniasis but also in promoting disease severity. Although candidate gene approaches …

Cutaneous leishmaniasis (CL) caused by Leishmania braziliensis is characterized by a
strong Th1 response that leads to skin lesion development. In areas where L. braziliensis …