All soluble proteins populate conformational ensembles that together constitute the native
state. Their fluctuations in water are intrinsic thermodynamic phenomena, and the …

Super-resolution microscopy (SRM) methods have allowed scientists to exceed the
diffraction limit of light, enabling the discovery and investigation of cellular structures at the …

Intrinsically disordered proteins (IDPs), which lack persistent structure, are a challenge to
structural biology due to the inapplicability of standard methods for characterization of folded …

Abstract The interface of protein structural biology, protein biophysics, molecular evolution,
and molecular population genetics forms the foundations for a mechanistic understanding of …

Intrinsically disordered regions (IDRs) are characterized by their lack of stable secondary or
tertiary structure and comprise a large part of the eukaryotic proteome. Although these …

The centrosome is a main orchestrator of the animal cellular microtubule cytoskeleton.
Dissecting its structure and assembly mechanisms has been a goal of cell biologists for over …

Interestingly, some protein domains are intrinsically disordered (abbreviated as IDD), and
the disorder degree of same domains may differ in different contexts. However, the …

Intrinsically disordered proteins (IDPs) are functional proteins that lack a well-defined three-
dimensional structure. The study of IDPs is a rapidly growing area as the crucial biological …

Studies of diverse phylogenetic lineages reveal that protein disorder increases in concert
with organismic complexity but that differences nevertheless exist among lineages. To gain …

Biomolecular condensates are membrane‐less assemblies of proteins and nucleic acids.
Centrosomes are biomolecular condensates that play a crucial role in nuclear division …