Gestational diabetes mellitus (GDM), characterized by a transitory form of diabetes induced
by insulin resistance and pancreatic β-cell dysfunction during pregnancy, has been …

Abstract The People's Republic of China (herein referred to as China) has witnessed one of
the most dramatic rises in diabetes prevalence anywhere in the world. The latest …

Extensive experimental animal studies and epidemiological observations have shown that
environmental influences during early development affect the risk of later pathophysiological …

The last three decades have witnessed an epidemic rise in the number of people with
diabetes, especially type 2 diabetes, and particularly in developing countries, where more …

There is an epidemic of diabetes in Asia. Type 2 diabetes develops in East Asian patients at
a lower mean body mass index (BMI) compared with those of European descent. At any …

Sex differences occur in most non-communicable diseases, including metabolic diseases,
hypertension, cardiovascular disease, psychiatric and neurological disorders and cancer. In …

Highlights•Leveraging health capital, even before conception, promotes resilience and
reduces later dependency on health care.•Biological and epigenetic processes operate …

Use of effective treatments and management programs is leading to longer survival of
people with diabetes. This, in combination with obesity, is thus contributing to a rise in …

The “developmental origins of health and disease”(DOHaD) is a concept that has emerged
over the past 50 years, linking the state of health and risk from disease in later childhood …

The prevalence of obesity and type 2 diabetes mellitus has increased rapidly over the past
few decades, and prevention efforts have not been successful. Fetal programming involves …