Epidemiology and clinical manifestations of immune thrombocytopenia
R Kohli, S Chaturvedi - Hämostaseologie, 2019 - thieme-connect.com
Immune thrombocytopenia (ITP) occurs with an incidence rate of 1.6 to 3.9 per 100,000
patient-years, which increases with age and has a slight female preponderance. ITP is …
patient-years, which increases with age and has a slight female preponderance. ITP is …
Advances in platelet function testing—light transmission aggregometry and beyond
J Le Blanc, F Mullier, C Vayne… - Journal of clinical …, 2020 - mdpi.com
Platelet function testing is essential for the diagnosis of hemostasis disorders. While there
are many methods used to test platelet function for research purposes, standardization is …
are many methods used to test platelet function for research purposes, standardization is …
Intravenous immunoglobulin vs observation in childhood immune thrombocytopenia: a randomized controlled trial
KMJ Heitink-Pollé, CSPM Uiterwaal… - Blood, The Journal …, 2018 - ashpublications.org
Management of children with newly diagnosed immune thrombocytopenia (ITP) consists of
careful observation or immunomodulatory treatment. Observational studies suggest a lower …
careful observation or immunomodulatory treatment. Observational studies suggest a lower …
Platelet function tests, independent of platelet count, are associated with bleeding severity in ITP
AL Frelinger III, RF Grace, AJ Gerrits… - Blood, The Journal …, 2015 - ashpublications.org
Immune thrombocytopenia (ITP) patients with similarly low platelet counts differ in their
tendency to bleed. To determine if differences in platelet function in ITP patients account for …
tendency to bleed. To determine if differences in platelet function in ITP patients account for …
Microbiota dysbiosis influences immune system and muscle pathophysiology of dystrophin‐deficient mice
A Farini, L Tripodi, C Villa, F Strati… - EMBO molecular …, 2023 - embopress.org
Duchenne muscular dystrophy (DMD) is a progressive severe muscle‐wasting disease
caused by mutations in DMD, encoding dystrophin, that leads to loss of muscle function with …
caused by mutations in DMD, encoding dystrophin, that leads to loss of muscle function with …
The role of platelets in bleeding in patients with thrombocytopenia and hematological disease
PJ Vinholt - Clinical Chemistry and Laboratory Medicine (CCLM), 2019 - degruyter.com
This review evaluates the role of platelets in bleeding risk among patients with
hematological disease and thrombocytopenia. Platelets are pivotal in primary hemostasis …
hematological disease and thrombocytopenia. Platelets are pivotal in primary hemostasis …
[HTML][HTML] Autoantibody-mediated desialylation impairs human thrombopoiesis and platelet lifespan
I Marini, J Zlamal, C Faul, U Holzer, S Hammer… - …, 2021 - ncbi.nlm.nih.gov
Immune thrombocytopenia is a common bleeding disease caused by autoantibody-
mediated accelerated platelet clearance and impaired thrombopoiesis. Accumulating …
mediated accelerated platelet clearance and impaired thrombopoiesis. Accumulating …
Diagnosis and management of immune thrombocytopenia in childhood
T Kühne - Hämostaseologie, 2017 - thieme-connect.com
Evidence-based medicine is growing in immune thrombocytopenia (ITP), but solid clinical
data are still lacking in many areas. A majority of children has self-limited ITP, but chronic …
data are still lacking in many areas. A majority of children has self-limited ITP, but chronic …
[HTML][HTML] Consensus report on flow cytometry for platelet function testing in thrombocytopenic patients: communication from the SSC of the ISTH
G Jourdi, S Ramström, R Sharma, T Bakchoul… - Journal of Thrombosis …, 2023 - Elsevier
Background Platelet count alone does not reliably predict bleeding risk, suggesting platelet
function is important to monitor in patients with thrombocytopenia. There is still an unmet …
function is important to monitor in patients with thrombocytopenia. There is still an unmet …
Pathophysiology of autoimmune thrombocytopenia: current insight with a focus on thrombopoiesis
I Marini, T Bakchoul - Hämostaseologie, 2019 - thieme-connect.com
Immune thrombocytopenia (ITP) is an autoimmune disease characterized by a significant
reduction in the number of circulating platelets which is frequently associated with bleeding …
reduction in the number of circulating platelets which is frequently associated with bleeding …