Cell–cell fusion remains the least understood type of membrane fusion process. However,
the last few years have brought about major advances in understanding fusion between …

Fertilization is the fusion of the male and female gamete. The process involves the fusion of
an oocyte with a sperm, creating a single diploid cell, the zygote, from which a new …

Fertilization occurs when sperm and egg recognize each other and fuse to form a new,
genetically distinct organism. The molecular basis of sperm–egg recognition is unknown, but …

Sperm− oocyte membrane fusion is one of the most important events for fertilization. So far,
IZUMO1 and Fertilization Influencing Membrane Protein (FIMP) on the sperm membrane …

CD9 belongs to the tetraspanin superfamily. Depending on the cell type and associated
molecules, CD9 has a wide variety of biological activities such as cell adhesion, motility …

Fertilization is an essential biological process in sexual reproduction and comprises a series
of molecular interactions between the sperm and egg,. The fusion of the haploid …

Fertilization is a fundamental process in sexual reproduction, creating a new individual
through the combination of male and female gametes,,,. The IZUMO1 sperm membrane …

Sperm–oocyte fusion is a critical event in mammalian fertilization, categorized by three
indispensable proteins. Sperm membrane protein IZUMO1 and its counterpart oocyte …

Three genes are known to be essential for gamete adhesion/fusion (Cd9, Izumo1 and Juno).
Here, we confirmed that Spaca6 null males are infertile and showed that their sperm …

Mammalian sperm–egg adhesion depends on the trans-interaction between the sperm-
specific type I glycoprotein IZUMO1 and its oocyte-specific GPI-anchored receptor JUNO …