Human anelloviruses: an update of molecular, epidemiological and clinical aspects

S Spandole, D Cimponeriu, LM Berca, G Mihăescu - Archives of virology, 2015 - Springer
Human torque teno viruses (TTVs) are new, emerging infectious agents, recently assigned
to the family Anelloviridae. The first representative of the genus, torque teno virus (TTV), was …

[HTML][HTML] Torquetenovirus: the human virome from bench to bedside

D Focosi, G Antonelli, M Pistello, F Maggi - Clinical Microbiology and …, 2016 - Elsevier
Torquetenovirus (TTV) is the most abundant component of human virome. Virologists have
long ignored this orphan and highly divergent virus, in part because TTV cannot be cultured …

The human virome: viral metagenomics, relations with human diseases, and therapeutic applications

GH Bai, SC Lin, YH Hsu, SY Chen - Viruses, 2022 - mdpi.com
The human body is colonized by a wide range of microorganisms. The field of viromics has
expanded since the first reports on the detection of viruses via metagenomic sequencing in …

Integrated immunologic monitoring in solid organ transplantation: the road toward torque Teno virus-guided immunosuppression

P Jaksch, I Görzer, E Puchhammer-Stöckl… - Transplantation, 2022 - journals.lww.com
Potent immunosuppressive drugs have been introduced into clinical care for solid organ
transplant recipients. It is now time to guide these drugs on an individual level to optimize …

[HTML][HTML] Torque teno virus for risk stratification of graft rejection and infection in kidney transplant recipients—a prospective observational trial

K Doberer, M Schiemann, R Strassl… - American Journal of …, 2020 - Elsevier
The nonpathogenic and ubiquitous torque teno virus (TTV) is associated with
immunosuppression in solid organ transplant recipients. Studies in kidney transplant …

Quantification of torque teno virus viremia as a prospective biomarker for infectious disease in kidney allograft recipients

R Strassl, M Schiemann, K Doberer… - The Journal of …, 2018 - academic.oup.com
Background Drug-induced immunosuppression following kidney transplantation is crucial to
prevent allograft rejection, but increases risk for infectious disease. Tailoring of drug dosing …

[HTML][HTML] Torque-Teno virus viral load as a potential endogenous marker of immune function in solid organ transplantation

O Rezahosseini, CH Drabe, SS Sørensen… - Transplantation …, 2019 - Elsevier
Solid organ transplantation (SOT) recipients receive immunosuppressive therapy to avoid
rejection of the transplanted organ. Immunosuppressive therapy increases the risk of …

Risk factors associated with the onset of relapsing‐remitting and primary progressive multiple sclerosis: a systematic review

KA McKay, V Kwan, T Duggan… - BioMed research …, 2015 - Wiley Online Library
Multiple sclerosis (MS) is a chronic central nervous system disease with a highly
heterogeneous course. The aetiology of MS is not well understood but is likely a …

Understanding torquetenovirus (TTV) as an immune marker

EJ Gore, L Gard, HGM Niesters… - Frontiers in …, 2023 - frontiersin.org
Torquetenovirus (TTV), a small, single stranded anellovirus, is currently being explored as a
marker of immunocompetence in patients with immunological impairment and inflammatory …

Viral infections in HSCT: detection, monitoring, clinical management, and immunologic implications

C Annaloro, F Serpenti, G Saporiti, G Galassi… - Frontiers in …, 2021 - frontiersin.org
In spite of an increasing array of investigations, the relationships between viral infections
and allogeneic hematopoietic stem cell transplantation (HSCT) are still controversial, and …