Hypoxia in aging and aging-related diseases: mechanism and therapeutic strategies

Y Wei, S Giunta, S Xia - International journal of molecular sciences, 2022 - mdpi.com
As the global aging process continues to lengthen, aging-related diseases (eg, chronic
obstructive pulmonary disease (COPD), heart failure) continue to plague the elderly …

A systematic review of electrocardiographic changes in healthy high-altitude populations

JB Parodi, R Ramchandani, Z Zhou, DX Chango… - Trends in …, 2023 - Elsevier
High-altitude environments are characterized by decreased atmospheric pressures at which
individuals exhibit a reduced volume of maximal oxygen uptake and arterial partial pressure …

Effect of a day-trip to altitude (2500 m) on exercise performance in pulmonary hypertension: randomised crossover trial

SR Schneider, LC Mayer, M Lichtblau… - ERJ Open …, 2021 - Eur Respiratory Soc
Question addressed by the study To investigate exercise performance and hypoxia-related
health effects in patients with pulmonary hypertension (PH) during a high-altitude sojourn …

[HTML][HTML] Smartwatch-Based Maximum Oxygen Consumption Measurement for Predicting Acute Mountain Sickness: Diagnostic Accuracy Evaluation Study

X Ye, M Sun, S Yu, J Yang, Z Liu, H Lv… - JMIR mHealth and …, 2023 - mhealth.jmir.org
Background: Cardiorespiratory fitness plays an important role in coping with hypoxic stress
at high altitudes. However, the association of cardiorespiratory fitness with the development …

Cardiorespiratory adaptation to short-term exposure to altitude vs. Normobaric hypoxia in patients with pulmonary hypertension

SR Schneider, M Lichtblau, M Furian, LC Mayer… - Journal of clinical …, 2022 - mdpi.com
Prediction of adverse health effects at altitude or during air travel is relevant, particularly in
pre-existing cardiopulmonary disease such as pulmonary arterial or chronic thromboembolic …

Clinician's corner: counseling patients with pulmonary vascular disease traveling to high altitude

S Ulrich, M Lichtblau, SR Schneider… - … Altitude Medicine & …, 2022 - liebertpub.com
Ulrich, Silvia, Mona Lichtblau, Simon R. Schneider, Stéphanie Saxer, and Konrad E. Bloch,
Clinician's corner: counseling patients with pulmonary vascular disease traveling to high …

[HTML][HTML] Prevalence of pulmonary hypertension in COPD patients living at high altitude

C Aguirre-Franco, CA Torres-Duque, G Salazar… - Pulmonology, 2022 - Elsevier
Background Pulmonary hypertension (PH) is associated with poor prognosis for patients
with chronic obstructive pulmonary disease (COPD). Most of the knowledge about PH in …

[HTML][HTML] Tensions in taxonomies: current understanding and future directions in the pathobiologic basis and treatment of group 1 and group 3 pulmonary hypertension

S Gu, K Goel, LM Forbes, VO Kheyfets… - Comprehensive …, 2023 - ncbi.nlm.nih.gov
In the over 100 years since the recognition of pulmonary hypertension (PH), immense
progress and significant achievements have been made with regard to understanding the …

Characteristics and risk profiles of patients with pulmonary arterial or chronic thromboembolic pulmonary hypertension living permanently at> 2500 m of high altitude …

R Hoyos, M Lichtblau, E Cajamarca… - Pulmonary …, 2024 - Wiley Online Library
Over 80 Mio people worldwide live> 2500 m, including at least as many patients with
pulmonary vascular disease (PVD), defined as pulmonary arterial or chronic …

Mechanisms and molecular targets of compound danshen dropping pill for heart disease caused by high altitude based on network Pharmacology and molecular …

J Yan, P Ruan, Y Ge, J Gao, H Tan, C Xiao, Q Gao… - ACS …, 2021 - ACS Publications
Compound Danshen dropping pill (CDDP), a famous Chinese medicine formula, has been
widely used to treat high-altitude heart disease in China. However, its molecular …