Nasal delivery as a strategy for the prevention and treatment of COVID-19

F Sonvico, G Colombo, E Quarta… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction The upper respiratory tract is a major route of infection for COVID-19 and other
respiratory diseases. Thus, it appears logical to exploit the nose as administration site to …

[HTML][HTML] Efficacy and effectiveness of influenza vaccination in healthy children. A review of current evidence

A Orrico-Sánchez, Á Valls-Arévalo… - … y microbiologia clinica …, 2023 - Elsevier
Influenza is common in healthy children and adolescents and is associated with a high rate
of hospitalization in this group, especially for those< 5 years. Although the WHO has …

Broad cross protection by recombinant live attenuated influenza H3N2 seasonal virus expressing conserved M2 extracellular domain in a chimeric hemagglutinin

BR Park, KH Kim, T Kotomina, MC Kim, YM Kwon… - Scientific Reports, 2021 - nature.com
Hemagglutinin (HA)-based current vaccines provide suboptimum cross protection. Influenza
A virus contains an ion channel protein M2 conserved extracellular domain (M2e), a target …

Nasal spray live attenuated influenza vaccine: the first experience in Italy in children and adolescents during the 2020–21 season

C Gasparini, M Acunzo, A Biuso, S Roncaglia… - Italian Journal of …, 2021 - Springer
Abstract Background In Italy only recently, for the 2020–21 season, has the flu vaccination
been extended to all children. A quadrivalent live attenuated influenza vaccine (qLAIV) was …

[HTML][HTML] Enhancing the cross protective efficacy of live attenuated influenza virus vaccine by supplemented vaccination with M2 ectodomain virus-like particles

YT Lee, KH Kim, EJ Ko, MC Kim, YN Lee, HS Hwang… - Virology, 2019 - Elsevier
Current influenza vaccines including live attenuated influenza virus (LAIV) provide
suboptimal protection against drift and potential pandemic strains. We hypothesized that …

Increased adherence to influenza vaccination among Palermo family pediatricians: a study on safety and compliance of qLAIV vaccination

C Costantino, F Tramuto, N Bonaccorso… - Italian Journal of …, 2024 - Springer
Background Influenza represents a serious public health threat, especially for the
management of severe cases and complications of the disease, requiring the …

Cost-Effectiveness of Intranasal Live-Attenuated Influenza Vaccine for Children: A Systematic Review

KSK Chan, CHL Wong, HCW Choi - Vaccines, 2022 - mdpi.com
Introduction: The public health burden of seasonal influenza is significant, and influenza
vaccination is the most effective preventive strategy. Nonetheless, the recommendation of …

Evaluating partial series childhood vaccination services in a mobile clinic setting

W Chen, SM Misra, F Zhou, LC Sahni… - Clinical …, 2020 - journals.sagepub.com
This study aims to evaluate the cost-benefit of vaccination services, mostly partial series
administration, provided by a mobile clinic program (MCP) in Houston for children of …

Cost-effectiveness of childhood influenza vaccination in Europe: results from a systematic review

S Boccalini, A Bechini, A Moscadelli… - Expert Review of …, 2021 - Taylor & Francis
Introduction: Influenza can be a significant public health problem. Nevertheless, it is
preventable through vaccination. Concerning the pediatric population, the recommendation …

Real-World Effectiveness of Live Attenuated vs. Inactivated Influenza Vaccines in Children

V Rigamonti, V Torri, SK Morris, F Ieva, C Giaquinto… - medRxiv, 2024 - medrxiv.org
Background and objectives: Quadrivalent live attenuated influenza vaccines (LAIV-4) offer
an alternative to inactivated influenza vaccines (IIV) for children aged 2-17 years, but data …