Emerging diversity in lipid–protein interactions
Membrane lipids interact with proteins in a variety of ways, ranging from providing a stable
membrane environment for proteins to being embedded in to detailed roles in complicated …
membrane environment for proteins to being embedded in to detailed roles in complicated …
Characterization of lipid–protein interactions and lipid-mediated modulation of membrane protein function through molecular simulation
The cellular membrane constitutes one of the most fundamental compartments of a living
cell, where key processes such as selective transport of material and exchange of …
cell, where key processes such as selective transport of material and exchange of …
CHARMM‐GUI Membrane Builder toward realistic biological membrane simulations
CHARMM‐GUI Membrane Builder, http://www. charmm‐gui. org/input/membrane, is a web‐
based user interface designed to interactively build all‐atom protein/membrane or …
based user interface designed to interactively build all‐atom protein/membrane or …
Viral membrane fusion: a dance between proteins and lipids
There are at least 21 families of enveloped viruses that infect mammals, and many contain
members of high concern for global human health. All enveloped viruses have a dedicated …
members of high concern for global human health. All enveloped viruses have a dedicated …
Fusion peptide of SARS-CoV-2 spike rearranges into a wedge inserted in bilayered micelles
RK Koppisetti, YG Fulcher… - Journal of the American …, 2021 - ACS Publications
The receptor binding and proteolysis of Spike of SARS-CoV-2 release its S2 subunit to
rearrange and catalyze viral-cell fusion. This deploys the fusion peptide for insertion into the …
rearrange and catalyze viral-cell fusion. This deploys the fusion peptide for insertion into the …
Perturbations of native membrane protein structure in alkyl phosphocholine detergents: a critical assessment of NMR and biophysical studies
Membrane proteins perform a host of vital cellular functions. Deciphering the molecular
mechanisms whereby they fulfill these functions requires detailed biophysical and structural …
mechanisms whereby they fulfill these functions requires detailed biophysical and structural …
[图书][B] The structure of biological membranes
PL Yeagle - 2004 - taylorfrancis.com
Recent research has provided an abundance of new information on membrane
biochemistry. Now more than ever, it is essential to update our current understanding of …
biochemistry. Now more than ever, it is essential to update our current understanding of …
Molecular dynamics, monte carlo simulations, and langevin dynamics: a computational review
Macromolecular structures, such as neuraminidases, hemagglutinins, and monoclonal
antibodies, are not rigid entities. Rather, they are characterised by their flexibility, which is …
antibodies, are not rigid entities. Rather, they are characterised by their flexibility, which is …
Characterization of a highly conserved domain within the severe acute respiratory syndrome coronavirus spike protein S2 domain with characteristics of a viral fusion …
IG Madu, SL Roth, S Belouzard, GR Whittaker - Journal of virology, 2009 - Am Soc Microbiol
Many viral fusion proteins are primed by proteolytic cleavage near their fusion peptides.
While the coronavirus (CoV) spike (S) protein is known to be cleaved at the S1/S2 boundary …
While the coronavirus (CoV) spike (S) protein is known to be cleaved at the S1/S2 boundary …
Comparison of protein force fields for molecular dynamics simulations
O Guvench, AD MacKerell - Molecular modeling of proteins, 2008 - Springer
In the context of molecular dynamics simulations of proteins, the term “force field” refers to
the combination of a mathematical formula and associated parameters that are used to …
the combination of a mathematical formula and associated parameters that are used to …