[HTML][HTML] Recent progress in the immunotherapy of hepatocellular carcinoma: Non-coding RNA-based immunotherapy may improve the outcome
Hepatocellular carcinoma (HCC) is the second most lethal cancer and a leading cause of
cancer-related mortality worldwide. Immune checkpoint inhibitors (ICIs) significantly …
cancer-related mortality worldwide. Immune checkpoint inhibitors (ICIs) significantly …
Research Progress on the Role of Epigenetic Methylation Modification in Hepatocellular Carcinoma
J Wang, W Gao, H Yu, Y Xu, C Bai… - Journal of …, 2024 - Taylor & Francis
Hepatocellular carcinoma (HCC) stands as the prevailing form of primary liver cancer,
characterized by a poor prognosis and high mortality rate. A pivotal factor in HCC …
characterized by a poor prognosis and high mortality rate. A pivotal factor in HCC …
[HTML][HTML] Construction of a T-cell exhaustion-related gene signature for predicting prognosis and immune response in hepatocellular carcinoma
T Kuang, L Zhang, D Chai, C Chen, W Wang - Aging (Albany NY), 2023 - ncbi.nlm.nih.gov
Background: Hepatocellular carcinoma (HCC) is a heterogeneous malignancy with a rising
prevalence worldwide. Immunotherapy has been shown to improve treatment outcomes for …
prevalence worldwide. Immunotherapy has been shown to improve treatment outcomes for …
Multi-cohort validation study of a four-gene signature for risk stratification and treatment response prediction in hepatocellular carcinoma
C Liu, Z Xiao, S Wu, Z Yang, G Ji, J Duan… - Computers in Biology …, 2023 - Elsevier
Background The intricate molecular landscape of hepatocellular carcinoma (HCC) presents
a significant challenge to achieving precise risk stratification through clinical genetic testing …
a significant challenge to achieving precise risk stratification through clinical genetic testing …
Multiscale network modeling reveals the gene regulatory landscape driving cancer prognosis in 32 cancer types
P Xu, B Zhang - Genome Research, 2023 - genome.cshlp.org
Cancer is a complex disease with diverse molecular mechanisms that affect patient
prognosis. Network-based approaches are effective in revealing a holistic picture of cancer …
prognosis. Network-based approaches are effective in revealing a holistic picture of cancer …
Identification of oncogenes and tumor-suppressor genes with hepatocellular carcinoma: A comprehensive analysis based on TCGA and GEO datasets
Y Zhu, Y Wang, M Hu, X Lu, G Sun - Frontiers in genetics, 2023 - frontiersin.org
Aim: Existing targeted therapies for hepatocellular carcinoma (HCC) are resistant and have
limitations. It is crucial to find new HCC-related target genes. Methods: RNA-sequencing …
limitations. It is crucial to find new HCC-related target genes. Methods: RNA-sequencing …
A Comprehensive Bioinformatic Analysis of RNA-seq Datasets Reveals a Differential and Variable Expression of Wildtype and Variant UGT1A Transcripts in Human …
Simple Summary UGT enzymes metabolize and detoxify numerous small molecules that are
important in cancer, including carcinogens, endogenous growth regulators, and anticancer …
important in cancer, including carcinogens, endogenous growth regulators, and anticancer …
Activation of Cryptic Donor Splice Sites within the UDP-Glucuronosyltransferase (UGT) 1A First-Exon Region Generates Variant Transcripts That Encode UGT1A …
The human UDP-glucuronosyltransferases (UGTs) have crucial roles in metabolizing and
clearing numerous small lipophilic compounds. The UGT1A locus generates nine UGT1A …
clearing numerous small lipophilic compounds. The UGT1A locus generates nine UGT1A …
Activation of Cryptic Donor Splice Sites Within the UGT1A First-Exon Region Generates Variant Transcripts That Encode UGT1A Proteins With Truncated Aglycone …
The human UDP-glucuronosyltransferases (UGTs) have crucial roles in metabolizing and
clearing numerous small lipophilic compounds. The UGT1A locus generates nine UGT1A …
clearing numerous small lipophilic compounds. The UGT1A locus generates nine UGT1A …
Unleashing the potential of gene signatures as prognostic and predictive tools: A step closer to personalized medicine in hepatocellular carcinoma (HCC)
A Pourbagheri‐Sigaroodi, F Fallah… - Cell Biochemistry …, 2024 - Wiley Online Library
Hepatocellular carcinoma (HCC) is one of the growing malignancies globally, affecting a
myriad of people and causing numerous cancer‐related deaths. Despite therapeutic …
myriad of people and causing numerous cancer‐related deaths. Despite therapeutic …