Cancer-derived exosomes: their role in cancer biology and biomarker development

VC Kok, CC Yu - International Journal of Nanomedicine, 2020 - Taylor & Francis
Exosomes are a subset of tiny extracellular vesicles manufactured by all cells and are
present in all body fluids. They are produced actively in tumor cells, which are released and …

Exosome-mediated metabolic reprogramming: the emerging role in tumor microenvironment remodeling and its influence on cancer progression

E Yang, X Wang, Z Gong, M Yu, H Wu… - Signal transduction and …, 2020 - nature.com
Metabolic reprogramming is reported to be one of the hallmarks of cancer, which is an
adaptive mechanism by which fast-growing cancer cells adapt to their increasing energy …

Effect of exosomal miRNA on cancer biology and clinical applications

Z Sun, K Shi, S Yang, J Liu, Q Zhou, G Wang, J Song… - Molecular cancer, 2018 - Springer
Exosomes, extracellular vesicles with diameters ranging from 30 to 150 nm, are widely
present in various body fluids. Recently, microRNAs (miRNAs) have been identified in …

[HTML][HTML] Advances in circular RNA and its applications

X Zhao, Y Zhong, X Wang, J Shen… - International Journal of …, 2022 - ncbi.nlm.nih.gov
Circular RNA (circRNA) is a novel endogenous non-coding RNA (ncRNA) that, like
microRNA (miRNA), is a rapidly emerging RNA research topic. CircRNA, unlike traditional …

[PDF][PDF] Endoplasmic reticulum stress causes liver cancer cells to release exosomal miR‐23a‐3p and up‐regulate programmed death ligand 1 expression in …

J Liu, L Fan, H Yu, J Zhang, Y He, D Feng, F Wang… - …, 2019 - Wiley Online Library
Endoplasmic reticulum (ER) stress promotes tumor cell escape from immunosurveillance.
However, the underlying mechanisms remain unknown. We hypothesized that ER stress …

The role of exosomes and exosomal microRNA in cardiovascular disease

D Zheng, M Huo, B Li, W Wang, H Piao… - Frontiers in cell and …, 2021 - frontiersin.org
Exosomes are small vesicles (30–150 nm in diameter) enclosed by a lipid membrane
bilayer, secreted by most cells in the body. They carry various molecules, including proteins …

An overview of microRNAs

SM Hammond - Advanced drug delivery reviews, 2015 - Elsevier
The discovery of the first microRNA (miRNA) over 20 years ago has ushered in a new era in
molecular biology. There are now over 2000 miRNAs that have been discovered in humans …

Field-free isolation of exosomes from extracellular vesicles by microfluidic viscoelastic flows

C Liu, J Guo, F Tian, N Yang, F Yan, Y Ding, JY Wei… - ACS …, 2017 - ACS Publications
Exosomes, molecular cargos secreted by almost all mammalian cells, are considered as
promising biomarkers to identify many diseases including cancers. However, the small size …

Ectosomes and exosomes: shedding the confusion between extracellular vesicles

E Cocucci, J Meldolesi - Trends in cell biology, 2015 - cell.com
Long-and short-distance communication can take multiple forms. Among them are
exosomes and ectosomes, extracellular vesicles (EVs) released from the cell to deliver …

Role of exosomal proteins in cancer diagnosis

W Li, C Li, T Zhou, X Liu, X Liu, X Li, D Chen - Molecular cancer, 2017 - Springer
Exosomes are emerging as a new type of cancer biomarkers. Exosome is a bilayered nano-
sized vesicle secreted by various living cells in all body fluids. Based on the expanding …