Cancer cell genetics shaping of the tumor microenvironment reveals myeloid cell-centric exploitable vulnerabilities in hepatocellular carcinoma
CFA Ramirez, D Taranto, M Ando-Kuri… - Nature …, 2024 - nature.com
Myeloid cells are abundant and plastic immune cell subsets in the liver, to which pro-
tumorigenic, inflammatory and immunosuppressive roles have been assigned in the course …
tumorigenic, inflammatory and immunosuppressive roles have been assigned in the course …
RSK2 inactivation cooperates with AXIN1 inactivation or β-catenin activation to promote hepatocarcinogenesis
S Schaeffer, B Gupta, AL Calatayud, J Calderaro… - Journal of …, 2023 - Elsevier
Background & Aims Recurrent somatic mutations of the RPS6KA3 gene encoding for the
serine/threonine kinase RSK2 were identified in hepatocellular carcinomas (HCCs) …
serine/threonine kinase RSK2 were identified in hepatocellular carcinomas (HCCs) …