Dendrimers in combination with natural products and analogues as anti-cancer agents

S Mignani, J Rodrigues, H Tomas… - Chemical Society …, 2018 - pubs.rsc.org
For the first time, an overview of dendrimers in combination with natural products and
analogues as anti-cancer agents is presented. This reflects the development of drug delivery …

Recent status of nanomaterial fabrication and their potential applications in neurological disease management

KS Siddiqi, A Husen, SS Sohrab, MO Yassin - Nanoscale research letters, 2018 - Springer
Nanomaterials (NMs) are receiving remarkable attention due to their unique properties and
structure. They vary from atoms and molecules along with those of bulk materials. They can …

Lactoferrin coupled lower generation PAMAM dendrimers for brain targeted delivery of memantine in aluminum-chloride-induced Alzheimer's disease in mice

A Gothwal, H Kumar, KT Nakhate, Ajazuddin… - Bioconjugate …, 2019 - ACS Publications
Lower generation PAMAM dendrimers have an immense potential for drug delivery with
lower toxicity, but these dendrimers yet need certain basic ameliorations. In this study, the …

Dendrimers in neurodegenerative diseases

MD Pérez-Carrión, I Posadas - Processes, 2023 - mdpi.com
Neurodegenerative diseases (NDs), such as Parkinson's Disease (PD), Alzheimer's Disease
(AD), Multiple Sclerosis (MS) and amyotrophic lateral sclerosis (ALS), are characterized by …

Phosphorus dendrimers for nanomedicine

AM Caminade - Chemical Communications, 2017 - pubs.rsc.org
From biomaterials to imaging, and from drug delivery to drugs by themselves, phosphorus-
containing dendrimers offer a large palette of biological properties, depending essentially on …

[HTML][HTML] Dendrimers and derivatives as multifunctional nanotherapeutics for Alzheimer's disease

DA Moreira, SD Santos, V Leiro, AP Pêgo - Pharmaceutics, 2023 - mdpi.com
Alzheimer's disease (AD) is the most prevalent form of dementia. It affects more than 30
million people worldwide and costs over US $1.3 trillion annually. AD is characterized by the …

Revisiting cationic phosphorus dendrimers as a nonviral vector for optimized gene delivery toward cancer therapy applications

L Chen, J Li, Y Fan, J Qiu, L Cao, R Laurent… - …, 2020 - ACS Publications
Gene delivery, one important cancer-therapy mode, still remains to be challenging because
of the shortage of highly efficient and safe nonviral vectors. Here, we revisit the development …

[HTML][HTML] Dendrimers in Alzheimer's disease: recent approaches in multi-targeting strategies

C Arbez-Gindre, BR Steele, M Micha-Screttas - Pharmaceutics, 2023 - mdpi.com
Nanomaterials play an increasingly important role in current medicinal practice. As one of
the most significant causes of human mortality, and one that is increasing year by year …

Alzheimer's disease–future therapy based on dendrimers

G Aliev, GM Ashraf, VV Tarasov… - Current …, 2019 - ingentaconnect.com
Alzheimer's disease (AD) is characterized by the loss of neurons. It is the most common
cause of dementia in the elderly population accompanied by pathological degeneration of …

Dendrimer architectonics to treat cancer and neurodegenerative diseases with implications in theranostics and personalized medicine

H Moorthy, T Govindaraju - ACS Applied Bio Materials, 2021 - ACS Publications
Integration of diagnostic and therapeutic functions in a single platform namely theranostics
has become a cornerstone for personalized medicine. Theranostics platform facilitates …