Abnormalities in B cells play pivotal roles in the pathogenesis of systemic lupus
erythematosus (SLE) and lupus nephritis (LN). Breach in central and peripheral tolerance …

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by the
presence of autoantibodies against nuclear antigens, immune complex deposition, and …

Systemic lupus erythematosus is a chronic autoimmune disease characterized by loss of
tolerance against nuclear and cytoplasmic self-antigens, induction of immunity and tissue …

A powerful interaction between the autonomic and the immune systems plays a prominent
role in the initiation and maintenance of hypertension and significantly contributes to …

Objective Systemic lupus erythematosus (SLE), the most common form of lupus, is a
multisystemic rheumatic disease with different clinical features that generally affect women …

Aim To determine the role of IL-17 and IL-6 in the pathogenesis of SLE as biomarkers of
disease activity and predictors of remission and outcome of therapy in patients with active …

Objective The abnormal formation and insufficient clearance of neutrophil extracellular traps
(NETs) has been reported to be involved in the pathogenesis of lupus nephritis (LN). The …

Background Identification of universal biomarkers to predict systemic lupus erythematosus
(SLE) flares is challenging due to the heterogeneity of the disease. Several biomarkers have …

Systemic lupus erythematosus (SLE) is a complicated autoimmune disease of multifactorial
pathoaetiology. One of the most serious manifestations is lupus nephritis. The pathogenesis …

Recent evidence suggests the existence of a nexus between inflammatory pathways and the
female sex hormone 17β-estradiol, resulting in increased interferon-stimulated genes …