Single-cell RNA sequencing technology landscape in 2023

HQ Qu, C Kao, H Hakonarson - Stem Cells, 2024 - academic.oup.com
Single-cell RNA sequencing (scRNA-seq) has revolutionized our understanding of cellular
heterogeneity and the dynamics of gene expression, bearing profound significance in stem …

Single-cell transcriptomics is revolutionizing the improvement of plant biotechnology research: recent advances and future opportunities

H Kaur, P Jha, SJ Ochatt, V Kumar - Critical Reviews in …, 2024 - Taylor & Francis
Single-cell approaches are a promising way to obtain high-resolution transcriptomics data
and have the potential to revolutionize the study of plant growth and development. Recent …

[HTML][HTML] New technologies to study helminth development and host-parasite interactions

C Britton, R Laing, TN McNeilly, MG Perez… - International journal for …, 2023 - Elsevier
How parasites develop and survive, and how they stimulate or modulate host immune
responses are important in understanding disease pathology and for the design of new …

Single-nucleus chromatin landscape dataset of mouse brain development and aging

Y Ma, S Guo, Y Chen, Y Peng, X Su, H Jiang, X Lin… - Scientific Data, 2024 - nature.com
The development and aging of the brain constitute a lifelong dynamic process, marked by
structural and functional changes that entail highly coordinated cellular differentiation and …

Machine learning: a tool to shape the future of medicine

O Hazapi, N Lagopati, VC Pezoulas… - Handbook of Machine …, 2022 - Springer
The constant evolution of biomedicine, biophysics and biochemistry has enabled scientists
to investigate and study each cell identity via analyzing the transciptome and its kinetics, the …

A single-cell eQTL atlas of the human cerebellum reveals vulnerability of oligodendrocytes in essential tremor

CE Castonguay, F Aboasali, M Medeiros, T Becret… - bioRxiv, 2024 - biorxiv.org
Essential tremor (ET) is a movement disorder characterized by an upper-limb postural and
action tremor. It is one of the most common neurological disorders, affecting 1% of the …

Endolysosomal dysfunction in radial glia progenitor cells leads to defective cerebral angiogenesis and compromised Blood-Brain Barrier integrity

I Bassi, M Grunspan, G Hen, KA Ravichandran… - BioRxiv, 2023 - biorxiv.org
The neurovascular unit (NVU) is a complex structure comprising neurons, glia, and pericytes
that interact with specialized endothelial cells to maintain cerebral homeostasis and blood …

A single-cell eQTL atlas of the human cerebellum reveals vulnerability of oligodendrocytes in essential tremor

G Rouleau, CE Castonguay, F Aboasali, M Medeiros… - 2024 - researchsquare.com
Essential tremor (ET) is a movement disorder characterized by an upper-limb postural and
action tremor. It is one of the most common neurological disorders, affecting 1% of the …

VData: Temporally annotated data manipulation and storage

M Bouvier, A Bonnaffoux - bioRxiv, 2023 - biorxiv.org
Background: Recent advances in both single-cell sequencing technologies and gene
expression simulation algorithms have led to the production of increasingly large datasets …

Computational approach to characterize gene dynamics using bulk and single-nucleus RNA sequencing to study Alzheimer's disease

N Rezaie - 2024 - escholarship.org
The brain is a complex organ that controls thought, memory, emotion, touch, motor skills,
vision, breathing, temperature, hunger, and many processes that regulate our body …