Pathogenesis of cancers derived from thyroid follicular cells
The genomic simplicity of differentiated cancers derived from thyroid follicular cells offers
unique insights into how oncogenic drivers impact tumour phenotype. Essentially, the main …
unique insights into how oncogenic drivers impact tumour phenotype. Essentially, the main …
Thyroid autoimmune disorders and cancer
SM Ferrari, P Fallahi, G Elia, F Ragusa, I Ruffilli… - Seminars in cancer …, 2020 - Elsevier
In the last decades, many studies conducted in vitro, and in vivo, have shown that thyroid
autoimmunity and thyroid cancer (TC)(mainly papillary TC) can be concomitant, even if the …
autoimmunity and thyroid cancer (TC)(mainly papillary TC) can be concomitant, even if the …
Small effects: The indispensable foundation for a cumulative psychological science
FM Götz, SD Gosling… - … on psychological science, 2022 - journals.sagepub.com
We draw on genetics research to argue that complex psychological phenomena are most
likely determined by a multitude of causes and that any individual cause is likely to have …
likely determined by a multitude of causes and that any individual cause is likely to have …
LncRNA SLC26A4-AS1 suppresses the MRN complex-mediated DNA repair signaling and thyroid cancer metastasis by destabilizing DDX5
J Yuan, Y Song, W Pan, Y Li, Y Xu, M Xie, Y Shen… - Oncogene, 2020 - nature.com
Lymph node metastasis is the major adverse feature for recurrence and death of thyroid
cancer patients. To identify lncRNAs involved in thyroid cancer metastasis, we systemically …
cancer patients. To identify lncRNAs involved in thyroid cancer metastasis, we systemically …
Genotyping of circulating tumor DNA in cholangiocarcinoma reveals diagnostic and prognostic information
TJ Ettrich, D Schwerdel, A Dolnik, F Beuter, TJ Blätte… - Scientific reports, 2019 - nature.com
Diagnosis of Cholangiocarcinoma (CCA) is difficult, thus a noninvasive approach towards (i)
assessing and (ii) monitoring the tumor-specific mutational profile is desirable to improve …
assessing and (ii) monitoring the tumor-specific mutational profile is desirable to improve …
Yap governs a lineage-specific neuregulin1 pathway-driven adaptive resistance to RAF kinase inhibitors
MER Garcia-Rendueles, G Krishnamoorthy… - Molecular Cancer, 2022 - Springer
Abstract Background Inactivation of the Hippo pathway promotes Yap nuclear translocation,
enabling execution of a transcriptional program that induces tissue growth. Genetic lesions …
enabling execution of a transcriptional program that induces tissue growth. Genetic lesions …
Current knowledge of germline genetic risk factors for the development of non-medullary thyroid cancer
K Hińcza, A Kowalik, A Kowalska - Genes, 2019 - mdpi.com
The thyroid is the most common site of endocrine cancer. One type of thyroid cancer, non-
medullary thyroid cancer (NMTC), develops from follicular cells and represents …
medullary thyroid cancer (NMTC), develops from follicular cells and represents …
Septin11 promotes hepatocellular carcinoma cell motility by activating RhoA to regulate cytoskeleton and cell adhesion
L Fu, X Wang, Y Yang, MH Chen, A Kuerban… - Cell Death & …, 2023 - nature.com
Septins as GTPases in the cytoskeleton, are linked to a broad spectrum of cellular functions,
including cell migration and the progression of hepatocellular carcinoma (HCC). However …
including cell migration and the progression of hepatocellular carcinoma (HCC). However …
Heavy metals in the environment and thyroid cancer
F Gianì, R Masto, MA Trovato, P Malandrino, M Russo… - Cancers, 2021 - mdpi.com
Simple Summary Epidemiological observations indicate that the incidence of thyroid cancer
is increased in volcanic areas. Indeed, in the volcanic area of Sicily, where residents are …
is increased in volcanic areas. Indeed, in the volcanic area of Sicily, where residents are …
Genome-wide association studies of autoimmune thyroid diseases, thyroid function, and thyroid cancer
Thyroid diseases, including autoimmune thyroid diseases and thyroid cancer, are known to
have high heritability. Family and twin studies have indicated that genetics plays a major …
have high heritability. Family and twin studies have indicated that genetics plays a major …