There have been numerous advances in all aspects of the carcinoid-syndrome, which is the
most common functional syndrome neuroendocrine tumors produce. These advances are …

Making a firm diagnosis of chronic heart failure with preserved ejection fraction (HFpEF)
remains a challenge. We recommend a new stepwise diagnostic process, the 'HFA–PEFF …

Carcinoid heart disease (CHD) is a rare and potentially lethal manifestation of an advanced
carcinoid (neuroendocrine) tumor. The pathophysiology of CHD is related to vasoactive …

Cardio-Oncology is a rapidly growing sub-specialty of medicine, however, there is very
limited guidance on the use of cardiac CT (CCT) in the care of Cardio-Oncology patients. In …

Neuroendocrine tumors (NETs) originate from the neuroendocrine cell system in the
bronchial and gastrointestinal tract and can produce hormones leading to distinct clinical …

The main focus of cardio-oncology has been the prevention and treatment of the cardiac
toxicity of chemotherapy and radiotherapy. Furthermore, several targeted therapies have …

Toxicity is a major cause of attrition in the development of pharmaceuticals, and the off-target
effects are a frequent contributor. The 5-HT2B receptor agonism is known to be responsible …

Background: Small intestinal neuroendocrine tumors are the most common of small bowel
malignancies with a clinical incidence of about 1 per 100,000 persons per year. There has …

Simple Summary A relevant proportion of patients with neuroendocrine tumors (NET)
develop carcinoid heart disease (CHD). This rare cardiac condition leads to worsened …

Heart valve disease (HVD) is a complex entity made by different pathological processes that
ultimately lead to the abnormal structure and disorganization of extracellular matrix proteins …