Beyond antibiotics: phage-encoded lysins against Gram-negative pathogens
Antibiotics remain the frontline agents for treating deadly bacterial pathogens. However, the
indiscriminate use of these valuable agents has led to an alarming rise in AMR. The …
indiscriminate use of these valuable agents has led to an alarming rise in AMR. The …
Development and characterization of HCMV recombinant subunit vaccines based on T-cell epitopes
J Li, X Li, F Liu, S Jiang, S Zhang, M Yu, W Liu, Z Li… - Vaccine, 2024 - Elsevier
Human cytomegalovirus (HCMV), a ubiquitous β-herpes virus, mostly causes asymptomatic
infections in adults with healthy immune systems. Due to immunosuppressive therapy, solid …
infections in adults with healthy immune systems. Due to immunosuppressive therapy, solid …
Characterization and Comparative Genomic Analysis of a Deep-Sea Bacillus Phage Reveal a Novel Genus
Y Chen, T Zhang, Q Lai, M Zhang, M Yu, R Zeng, M Jin - Viruses, 2023 - mdpi.com
As the most abundant biological entities, viruses are the major players in marine
ecosystems. However, our knowledge on virus diversity and virus–host interactions in the …
ecosystems. However, our knowledge on virus diversity and virus–host interactions in the …
Complete Genome Analyses of a Novel Flexivirus with Unique Genome Organization and Three Endornaviruses Hosted by the Mycorrhizal Fungus Terfezia claveryi
The extensive use of high-throughput sequencing (HTS) has significantly advanced and
transformed our comprehension of virus diversity, especially in intricate settings like soil and …
transformed our comprehension of virus diversity, especially in intricate settings like soil and …
Insights into the genomic features, lifestyle and therapeutic potential of B1 sub-cluster mycobacteriophages
Background A large number (about 1200) of mycobacteriophages (phages) have been
isolated on Mycobacterium smegmatis mc2155. Their genome analysis shows high …
isolated on Mycobacterium smegmatis mc2155. Their genome analysis shows high …
[HTML][HTML] Unlocking prophage potential: In silico and experimental analysis of a novel Mycobacterium fortuitum LysinB containing a peptidoglycan-binding domain
Endolysins are highly evolved bacteriophage-encoded lytic enzymes produced to damage
the bacterial cell wall for phage progeny release. They offer promising potential as highly …
the bacterial cell wall for phage progeny release. They offer promising potential as highly …
Investigation of the Structural Mechanisms of a Bacterial Clamp Loader
JT Landeck - 2024 - repository.escholarship.umassmed …
The sliding clamp is an integral protein in DNA replication and repair, where it increases the
speed of DNA synthesis and serves as a scaffold for repair proteins. Since the sliding clamp …
speed of DNA synthesis and serves as a scaffold for repair proteins. Since the sliding clamp …