The clinical and economic burden of chronic obstructive pulmonary disease in the USA

AJ Guarascio, SM Ray, CK Finch… - … and Outcomes Research, 2013 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is the third most common cause of death in
the USA. In 2010, the cost of COPD in the USA was projected to be approximately US …

The global impact of non-communicable diseases on healthcare spending and national income: a systematic review

T Muka, D Imo, L Jaspers, V Colpani, L Chaker… - European journal of …, 2015 - Springer
The impact of non-communicable diseases (NCDs) in populations extends beyond ill-health
and mortality with large financial consequences. To systematically review and meta-analyze …

Managing comorbidities in COPD

G Hillas, F Perlikos, I Tsiligianni… - International journal of …, 2015 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality
worldwide. Age and smoking are common risk factors for COPD and other illnesses, often …

Global burden of COPD: risk factors, prevalence, and future trends

DM Mannino, AS Buist - The Lancet, 2007 - thelancet.com
Chronic obstructive pulmonary disease (COPD) continues to be an important cause of
morbidity, mortality, and health-care costs worldwide. It is a global health issue, with …

Severe acute exacerbations and mortality in patients with chronic obstructive pulmonary disease

JJ Soler-Cataluña, MÁ Martínez-García, PR Sánchez… - Thorax, 2005 - thorax.bmj.com
Background: Patients with chronic obstructive pulmonary disease (COPD) often present with
severe acute exacerbations requiring hospital treatment. However, little is known about the …

Increased risk of exacerbation and hospitalization in subjects with an overlap phenotype: COPD-asthma

AMB Menezes, MM de Oca, R Pérez-Padilla… - Chest, 2014 - Elsevier
Background Several COPD phenotypes have been described; the COPD-asthma overlap is
one of the most recognized. The aim of this study was to evaluate the prevalence of three …

A comprehensive care management program to prevent chronic obstructive pulmonary disease hospitalizations: a randomized, controlled trial

VS Fan, JM Gaziano, R Lew, J Bourbeau… - Annals of internal …, 2012 - acpjournals.org
Background: Improving a patient's ability to self-monitor and manage changes in chronic
obstructive pulmonary disease (COPD) symptoms may improve outcomes. Objective: To …

Heart failure and chronic obstructive pulmonary disease: the challenges facing physicians and health services

NM Hawkins, S Virani, C Ceconi - European heart journal, 2013 - academic.oup.com
Pulmonary disease is common in patients with heart failure, through shared risk factors and
pathophysiological mechanisms. Adverse pulmonary vascular remodelling and chronic …

Ambroxol in the 21st century: pharmacological and clinical update

M Malerba, B Ragnoli - Expert opinion on drug metabolism & …, 2008 - Taylor & Francis
Background: Belonging to the group of expectorants, ambroxol is an active substance with a
long history that influences parameters considered to be the basis for the physiological …

Cost-of-illness studies: a review of current methods

E Akobundu, J Ju, L Blatt, CD Mullins - Pharmacoeconomics, 2006 - Springer
The number of cost-of-illness (COI) studies has expanded considerably over time. One
outcome of this growth is that the reported COI estimates are inconsistent across studies …