Pathogenesis of pneumonia and acute lung injury

ME Long, RK Mallampalli, JC Horowitz - Clinical Science, 2022 - portlandpress.com
Pneumonia and its sequelae, acute lung injury, present unique challenges for pulmonary
and critical care healthcare professionals, and these challenges have recently garnered …

The history and mystery of alveolar epithelial type II cells: focus on their physiologic and pathologic role in lung

B Ruaro, F Salton, L Braga, B Wade… - International journal of …, 2021 - mdpi.com
Alveolar type II (ATII) cells are a key structure of the distal lung epithelium, where they exert
their innate immune response and serve as progenitors of alveolar type I (ATI) cells …

Lung epithelial and endothelial damage, loss of tissue repair, inhibition of fibrinolysis, and cellular senescence in fatal COVID-19

F D'Agnillo, KA Walters, Y Xiao, ZM Sheng… - Science translational …, 2021 - science.org
Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), is characterized by respiratory distress, multiorgan …

Dysbiosis of the gut and lung microbiome has a role in asthma

K Hufnagl, I Pali-Schöll, F Roth-Walter… - Seminars in …, 2020 - Springer
Worldwide 300 million children and adults are affected by asthma. The development of
asthma is influenced by environmental and other exogenous factors synergizing with …

Pulmonary surfactant: a mighty thin film

F Possmayer, YY Zuo, RAW Veldhuizen… - Chemical …, 2023 - ACS Publications
Pulmonary surfactant is a critical component of lung function in healthy individuals. It
functions in part by lowering surface tension in the alveoli, thereby allowing for breathing …

Integrative physiology of pneumonia

LJ Quinton, AJ Walkey, JP Mizgerd - Physiological reviews, 2018 - journals.physiology.org
Pneumonia is a type of acute lower respiratory infection that is common and severe. The
outcome of lower respiratory infection is determined by the degrees to which immunity is …

[HTML][HTML] Respiratory syncytial virus: A comprehensive review of transmission, pathophysiology, and manifestation

J Kaler, A Hussain, K Patel, T Hernandez, S Ray - Cureus, 2023 - ncbi.nlm.nih.gov
With an increasing global incidence in children younger than the age of five, respiratory
syncytial virus (RSV) is one of the most common viral respiratory infections worldwide …

Single-cell analysis of shared signatures and transcriptional diversity during zebrafish development

A Sur, Y Wang, P Capar, G Margolin, MK Prochaska… - Developmental Cell, 2023 - cell.com
During development, animals generate distinct cell populations with specific identities,
functions, and morphologies. We mapped transcriptionally distinct populations across …

Hypoxia and innate immunity: keeping up with the HIFsters

SP Colgan, GT Furuta, CT Taylor - Annual review of …, 2020 - annualreviews.org
Recent years have witnessed an emergence of interest in understanding metabolic changes
associated with immune responses, termed immunometabolism. As oxygen is central to all …

All‐inkjet‐printed 3D alveolar barrier model with physiologically relevant microarchitecture

D Kang, JA Park, W Kim, S Kim, HR Lee… - Advanced …, 2021 - Wiley Online Library
With the outbreak of new respiratory viruses and high mortality rates of pulmonary diseases,
physiologically relevant models of human respiratory system are urgently needed to study …