Biomimetic materials have emerged as attractive and competitive alternatives for tissue
engineering (TE) and regenerative medicine. In contrast to conventional biomaterials or …

Metabolic engineering aims to improve the production of economically valuable molecules
through the genetic manipulation of microbial metabolism. While the discipline is a little over …

Concerns over climate change have necessitated a rethinking of our transportation
infrastructure. One possible alternative to carbon-polluting fossil fuels is biofuels produced …

Retrobiosynthesis provides an effective and sustainable approach to producing functional
molecules. The past few decades have witnessed a rapid expansion of biosynthetic …

Through advanced mechanistic modeling and the generation of large high-quality datasets,
machine learning is becoming an integral part of understanding and engineering living …

Abstract Machine learning provides researchers a unique opportunity to make metabolic
engineering more predictable. In this review, we offer an introduction to this discipline in …

The metabolome of an organism depends on environmental factors and intracellular
regulation and provides information about the physiological conditions. Metabolomics helps …

Metabolic engineering encompasses several widely-used strategies, which currently hold a
high seat in the field of biotechnology when its potential is manifesting through a plethora of …

Highlights•Application of machine learning in biotechnology is becoming essential.•Machine
learning is increasingly applied to advance systems metabolic engineering.•Machine …

Ectoine, a compatible solute synthesized by many halophiles for hypersalinity resistance,
has been successfully produced by metabolically engineered Halomonas bluephagenesis …