Importance The prevalence of irritable bowel syndrome (IBS) in the United States is between
7% and 16%, most common in women and young people, with annual direct costs estimated …

Irritable bowel syndrome (IBS) is a common functional bowel disorder characterised by
symptoms of recurrent abdominal pain associated with a change in bowel habit. This …

Bile acids (BAs) are the central signals in enterohepatic communication, and they also
integrate microbiota-derived signals into enterohepatic signaling. The tissue distribution and …

Background & Aims Bile acid diarrhea (BAD) affects approximately a quarter of patients with
irritable bowel syndrome with diarrhea (IBS-D). We aimed to compare the demographics …

Background Bile acid diarrhoea is often missed because gold standard nuclear medicine
tauroselcholic [75‐Se] acid (SeHCAT) testing has limited availability. Empirical treatment …

A sequence of consensus‐based Rome criteria for irritable bowel syndrome (IBS) has been
published since 1989. The fundamental definition based on abdominal pain in association …

Bile acid malabsorption (BAM) represents a common cause of chronic diarrhea whose
prevalence is under-investigated. We reviewed the evidence available regarding the …

Background Bile acids are central to enterohepatic signaling pathways activated through
natural receptors, farnesoid X receptor [FXR mediates synthesis of fibroblast growth factor …

Bile acid diarrhea (BAD) is characterized by increased frequency of bowel movements,
looser stool consistency, urgency, and need for proximity to toilet facilities owing to the …

Study Design In a single-center study, we prospectively collected fasting serum C4, a single,
random stool sample, and a 48-hour stool collection in healthy volunteers, patients with IBS …