Cancer is an abnormal state of cells where they undergo uncontrolled proliferation and
produce aggressive malignancies that causes millions of deaths every year. With the new …

Cancer has been a leading cause of death for decades. This dismal statistic has increased
efforts to prevent the disease or to detect it early, when treatment is less invasive, relatively …

Malignant transformation is characterized by dysregulation of diverse cellular processes that
have been the subject of detailed genetic, biochemical, and structural studies, but only …

The first wave of genetically targeted therapies for cancer focused on drugging gene
products that are recurrently mutated in specific cancer types. However, mutational analysis …

The antitumor efficiency and clinical translation of traditional nanomedicines is mainly
restricted by low drug loading, complex preparation technology, and potential toxicity …

Although photodynamic therapy (PDT) has promising advantages in almost non‐invasion,
low drug resistance, and low dark toxicity, it still suffers from limitations in the lipophilic …

Tumor microenvironment (TME) is generally featured by low pH values, high glutathione
(GSH) concentrations, overproduced hydrogen peroxide (H2O2), and severe hypoxia …

The urea functionality is inherent to numerous bioactive compounds, including a variety of
clinically approved therapies. Urea containing compounds are increasingly used in …

The past few years have witnessed the rise of chemodynamic therapy (CDT) as an emerging
strategy for malignant tumors suppression. Nanoplatform-based CDT has great potential …

Nanoparticulate drug delivery systems (Nano-DDSs) have emerged as possible solution to
the obstacles of anticancer drug delivery. However, the clinical outcomes and translation are …