Optimization of the hemolysis assay for the assessment of cytotoxicity

IP Sæbø, M Bjørås, H Franzyk, E Helgesen… - International journal of …, 2023 - mdpi.com
In vitro determination of hemolytic properties is a common and important method for
preliminary evaluation of cytotoxicity of chemicals, drugs, or any blood-contacting medical …

The E3 ligase adapter cereblon targets the C-terminal cyclic imide degron

S Ichikawa, HA Flaxman, W Xu, N Vallavoju, HC Lloyd… - Nature, 2022 - nature.com
The ubiquitin E3 ligase substrate adapter cereblon (CRBN) is a target of thalidomide and
lenalidomide, therapeutic agents used in the treatment of haematopoietic malignancies …

Review on oxidative stress relation on COVID-19: Biomolecular and bioanalytical approach

M Ebrahimi, P Norouzi, H Aazami… - International journal of …, 2021 - Elsevier
COVID-19 disease has put life of people in stress worldwide from many aspects. Since the
virus has mutated in absolutely short period of time the challenge to find a suitable vaccine …

Defining a role for hemoglobin in Parkinson's disease

J Freed, L Chakrabarti - npj Parkinson's Disease, 2016 - nature.com
Hemoglobin (Hb) has been shown to be expressed within dopaminergic neurons and to
have a role in maintaining iron and mitochondrial homeostasis. In Parkinson's disease …

Fabrication of BiCuOS nanoflowers acting as nanoarrays on photonic nanoparticles for chemo-photothermal therapy

S Ramamoorthy, RP Reji, SV Jayaraman… - Applied Surface …, 2023 - Elsevier
In recent years, 3D flower shaped nanostructures with an ability to improve internal photo
reflections and absorptions is gaining popularity for the development of photo-thermal heat …

Human hemoglobin structural and functional alterations and heme degradation upon interaction with benzene: a spectroscopic study

R Hosseinzadeh, AA Moosavi-Movahedi - Spectrochimica Acta Part A …, 2016 - Elsevier
Here, the effect of benzene on hemoglobin structure, stability and heme prosthetic group
integrity was studied by different methods. These included UV–vis absorption …

Interaction of insulin with methyl tert-butyl ether promotes molten globule-like state and production of reactive oxygen species

M Valipour, P Maghami, M Habibi-Rezaei… - International journal of …, 2015 - Elsevier
Interaction of methyl tert-butyl ether (MTBE) with proteins is a new look at its potential
adverse biological effects. When MTBE is released to the environment it enters the blood …

Sulfonamides stimulate ROS formation upon glycation of human carbonic anhydrase II

L Alaei, M Ashengroph… - International Journal of …, 2024 - Elsevier
Advanced glycation end products are the most important species of glycation pathway, and
cause disorders such as oxidative stress and diabetes. Sulfonamide compounds, which are …

Spectroscopic investigation on molecular aspects and structural and functional effects of tetraethyl pyrophosphate organophosphorus insecticide interaction with adult …

A Doroudian, R Hosseinzadeh, P Maghami… - Journal of …, 2022 - Taylor & Francis
Organophosphates are extremely toxic compounds that use extensively in agriculture and
household as insecticides. However, their binding mechanism to bio-macromolecules …

Counteraction of the deleterious effects of reactive oxygen species on hemoglobin structure and function by ellagic acid

M Valipour, P Maghami, M Habibi-Rezaei… - Journal of …, 2017 - Elsevier
Ellagic acid (EA) has been gaining a considerable attention in recent years. The interest in
non-drug and herbal base therapies is being increased. EA is a biological molecule found in …