The statins have been used for 30 years to prevent coronary artery disease and stroke. Their
primary mechanism of action is the lowering of serum cholesterol through inhibiting hepatic …

Cardiovascular diseases (CVDs) have been the prime cause of mortality worldwide for
decades. However, the underlying mechanism of their pathogenesis is not fully clear yet. It …

1–«МНОЦ МГУ им. МВ Ломоносова», 119192, Москва, Ломоносовский пр-кт, д. 27, корп.
10 2–ФГБОУ ВО «ПИМУ» МЗ РФ, 603950, Нижний Новгород, пл. Минина и Пожарского …

РЕКОМЕНДАЦИИ, СЕРДЕЧНАЯ НЕДОСТАТОЧНОСТЬ, ХРОНИЧЕСКАЯ СЕРДЕЧНАЯ
НЕДОСТАТОЧНОСТЬ, ОСТРАЯ ДЕКОМПЕНСАЦИЯ СЕРДЕЧНОЙ …

Background. Several studies have reported that statins have anti‐inflammatory effects.
Nevertheless, results of clinical trials concerning the effect of statins on the levels of C …

Inflammation is a key mechanism of cardiovascular diseases. It is an essential component of
atherosclerosis and a significant risk factor for the development of cardiovascular events. In …

▪ Abstract Statins are potent inhibitors of cholesterol biosynthesis. In clinical trials, statins are
beneficial in the primary and secondary prevention of coronary heart disease. However, the …

Background Large observational studies, small prospective studies and post-hoc analyses
of randomised clinical trials have suggested that statins could be beneficial in patients with …

Ample evidence exists in support of the potent anti-inflammatory properties of statins. In cell
studies and animal models statins exert beneficial cardiovascular effects. By inhibiting …

Cardiovascular disease (CVD), a major cause of mortality in the world, has been extensively
studied over the past decade. However, the exact mechanism underlying its pathogenesis …