Glioma targeted therapy: insight into future of molecular approaches

K Yang, Z Wu, H Zhang, N Zhang, W Wu, Z Wang… - Molecular Cancer, 2022 - Springer
Gliomas are the common type of brain tumors originating from glial cells. Epidemiologically,
gliomas occur among all ages, more often seen in adults, which males are more susceptible …

Epidemiology of glioblastoma multiforme–literature review

S Grochans, AM Cybulska, D Simińska, J Korbecki… - Cancers, 2022 - mdpi.com
Simple Summary Glioblastoma multiforme (GBM) is one of the most aggressive
malignancies, accounting for 14.5% of all central nervous system tumors and 48.6% of …

Genetic and biological hallmarks of colorectal cancer

J Li, X Ma, D Chakravarti, S Shalapour… - Genes & …, 2021 - genesdev.cshlp.org
Colorectal cancer has served as a genetic and biological paradigm for the evolution of solid
tumors, and these insights have illuminated early detection, risk stratification, prevention …

[HTML][HTML] Telomeres: history, health, and hallmarks of aging

D Chakravarti, KA LaBella, RA DePinho - Cell, 2021 - cell.com
The escalating social and economic burden of an aging world population has placed aging
research at center stage. The hallmarks of aging comprise diverse molecular mechanisms …

Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future …

PY Wen, M Weller, EQ Lee, BM Alexander… - Neuro …, 2020 - academic.oup.com
Glioblastomas are the most common form of malignant primary brain tumor and an important
cause of morbidity and mortality. In recent years there have been important advances in …

Diffuse glioma heterogeneity and its therapeutic implications

JG Nicholson, HA Fine - Cancer discovery, 2021 - AACR
Diffuse gliomas represent a heterogeneous group of universally lethal brain tumors
characterized by minimally effective genotype-targeted therapies. Recent advances have …

Clinical practice guidelines for the management of adult diffuse gliomas

T Jiang, DH Nam, Z Ram, W Poon, J Wang… - Cancer letters, 2021 - Elsevier
To follow the revision of the fourth edition of WHO classification and the recent progress on
the management of diffuse gliomas, the joint guideline committee of Chinese Glioma …

Genetic and molecular epidemiology of adult diffuse glioma

AM Molinaro, JW Taylor, JK Wiencke… - Nature Reviews …, 2019 - nature.com
The WHO 2007 glioma classification system (based primarily on tumour histology) resulted
in considerable interobserver variability and substantial variation in patient survival within …

Molecular targeted therapy of glioblastoma

E Le Rhun, M Preusser, P Roth, DA Reardon… - Cancer treatment …, 2019 - Elsevier
Glioblastomas are intrinsic brain tumors thought to originate from neuroglial stem or
progenitor cells. More than 90% of glioblastomas are isocitrate dehydrogenase (IDH) …

Current state of immunotherapy for glioblastoma

M Lim, Y Xia, C Bettegowda, M Weller - Nature reviews Clinical …, 2018 - nature.com
Glioma is the most common primary cancer of the central nervous system, and around 50%
of patients present with the most aggressive form of the disease, glioblastoma. Conventional …