The abilities of stem cells to self-renew and form different mature cells expand the
possibilities of applications in cell-based therapies such as tissue recomposition in …

Human-induced pluripotent stem cells (hiPSCs) have provided new methods to study
neurodegenerative diseases. In addition to their wide application in neuronal disorders …

A number of bioengineering strategies, using biophysical stimulation, are being explored to
guide the human mesenchymal stem cells (hMScs) into different lineages. In this context, we …

The apparent lack of success in curing cancer that was evidenced in the last four decades of
molecular medicine indicates the need for a global re-thinking both its nature and the …

Oligodendrocytes are fundamental for the functioning of the nervous system; they participate
in several cellular processes, including axonal myelination and metabolic maintenance for …

The concentration of intracellular calcium ion (Ca 2+) exhibits complex oscillations,
including bursting and chaos, as observed experimentally. These dynamics are influenced …

Ca 2+ oscillations, a widespread mode of cell signaling, were reported in non-excitable cells
for the first time more than 25 years ago. Their fundamental mechanism, based on the …

Endothelial progenitor cells (EPCs) are a sub‐population of bone marrow‐derived
mononuclear cells that are released in circulation to restore damaged endothelium during its …

All cells possess an innate ability to respond to a range of mechanical stimuli through their
complex internal machinery. This comprises various mechanosensory elements that detect …

Purpose The committed differentiation fate regulation has been a difficult problem in the
fields of stem cell research, evidence showed that nanomaterials could promote the …