Focal segmental glomerulosclerosis (FSGS) is a common glomerular disorder that manifests
clinically with the nephrotic syndrome and has a propensity to recur following kidney …

Viral infections frequently induce acute and chronic inflammatory diseases, yet the
contribution of the innate immune response to a detrimental host response remains poorly …

Background The signaling molecule stimulator of IFN genes (STING) was identified as a
crucial regulator of the DNA-sensing cyclic GMP-AMP synthase (cGAS)-STING pathway, and …

Background Adiponectin is an adipocytokine that plays a key regulatory role in glucose and
lipid metabolism in obesity. The prevalence of obesity has led to an increase in the …

IgA Nephropathy (IgAN) is a primary glomerulonephritis problem worldwide that develops
mainly in the 2nd and 3rd decade of life and reaches end-stage kidney disease after 20 …

After decades of primarily morphological study, positional cloning of the NPHS1 gene was
the landmark event that established aberrant podocyte genetics as a pivotal cause of …

Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis and
the leading cause of kidney failure in the world. The current widely accepted framework for …

The immune podocyte : Current Opinion in Rheumatology The immune podocyte : Current
Opinion in Rheumatology Log in or Register Subscribe to journalSubscribe Get new issue …

Glomerular podocytes are specialized in structure and play an essential role in glomerular
filtration. In addition, podocyte stress can initiate glomerular damage by inducing the injury …

Glomerular podocytes are highly specialized terminally differentiated cells that act as a
filtration barrier in the kidney. Mutations in the actin-binding protein, α-actinin 4 (ACTN4), are …