Intracranial outcomes of de novo brain metastases treated with osimertinib alone in patients with newly diagnosed EGFR-mutant NSCLC
Introduction Patients with EGFR-mutant NSCLC have a high incidence of brain metastases.
The EGFR-directed tyrosine kinase inhibitor osimertinib has intracranial activity, making the …
The EGFR-directed tyrosine kinase inhibitor osimertinib has intracranial activity, making the …
[HTML][HTML] Advancements without consensus: differing practice patterns highlight unanswered questions in the management of brain metastases from EGFR-and ALK …
C Hui, EL Pollom, G Li, NJ Myall - Journal of Thoracic Disease, 2023 - ncbi.nlm.nih.gov
In this recent issue of Journal of Thoracic Disease, Fong et al. describe practice patterns
pertaining to the management of asymptomatic brain metastases secondary to epidermal …
pertaining to the management of asymptomatic brain metastases secondary to epidermal …
Combined BBB-penetrant tyrosine kinase inhibitor and intracranial radiotherapy versus BBB-penetrant tyrosine kinase inhibitor alone for the treatment of EGFR …
Purpose This study was to determine whether combining blood-brain-barrier-penetrant
tyrosine kinase inhibitor (TKI), osimertinib, with intracranial radiotherapy (TKI+ RT) would …
tyrosine kinase inhibitor (TKI), osimertinib, with intracranial radiotherapy (TKI+ RT) would …
The indication of palliative whole-brain radiotherapy for patients with brain metastases: A simple prognostic scoring system in the era of stereotactic radiosurgery
T Hirose, S Deguchi, K Yasui, M Inoue, T Onoe… - 2024 - researchsquare.com
Background: Stereotactic irradiation has become the mainstay treatment for brain
metastases (BM), and whole-brain radiotherapy (WBRT) is often used for symptom …
metastases (BM), and whole-brain radiotherapy (WBRT) is often used for symptom …
[PDF][PDF] Perfusion parameters predict pathology and mutation status in lung cancer brain metastases based on CT imaging: a pilot study
C Jiang, X Liu, Q Qu, Z Jiang, Y Wang - 2022 - scholar.archive.org
Perfusion parameters predict pathology and mutation status in lung cancer brain metastases
based on CT imaging: a pilot study Page 1 Page 1/11 Perfusion parameters predict pathology …
based on CT imaging: a pilot study Page 1 Page 1/11 Perfusion parameters predict pathology …
[引用][C] Improved CNS Control With the Addition of Chemotherapy to Osimertinib—A Devil's Bargain?
We would like to congratulate Jänne et al 1 on publishing a detailed analysis of CNS
outcomes from the randomized phase III FLAURA2 study. Although many analyses did not …
outcomes from the randomized phase III FLAURA2 study. Although many analyses did not …