Isolation of a bacteriophage targeting Pseudomonas aeruginosa and exhibits a promising in vivo efficacy

A Abdelghafar, A El-Ganiny, G Shaker, M Askoura - AMB Express, 2023 - Springer
Pseudomonas aeruginosa is an important pathogen that causes serious infections. Bacterial
biofilms are highly resistant and render bacterial treatment very difficult, therefore …

From orphan phage to a proposed new family–the diversity of N4-like viruses

J Wittmann, D Turner, AD Millard, P Mahadevan… - Antibiotics, 2020 - mdpi.com
Escherichia phage N4 was isolated in 1966 in Italy and has remained a genomic orphan for
a long time. It encodes an extremely large virion-associated RNA polymerase unique for …

A novel virulent Litunavirus phage possesses therapeutic value against multidrug resistant Pseudomonas aeruginosa

V Lerdsittikul, M Thongdee… - Scientific Reports, 2022 - nature.com
Pseudomonas aeruginosa is a notable nosocomial pathogen that can cause severe
infections in humans and animals. The emergence of multidrug resistant (MDR) P …

Genomic and biochemical characterization of Acinetobacter podophage petty reveals a novel lysis mechanism and tail-associated depolymerase activity

AC Hernandez-Morales, LL Lessor, TL Wood… - Journal of …, 2018 - Am Soc Microbiol
The increased prevalence of drug-resistant, nosocomial Acinetobacter infections,
particularly from pathogenic members of the Acinetobacter calcoaceticus-baumannii …

Comparative Analysis of 37 Acinetobacter Bacteriophages

D Turner, HW Ackermann, AM Kropinski, R Lavigne… - Viruses, 2017 - mdpi.com
Members of the genus Acinetobacter are ubiquitous in the environment and the multiple-
drug resistant species A. baumannii is of significant clinical concern. This clinical relevance …

Comparative genomics defines the core genome of the growing N4-like phage genus and identifies N4-like Roseophage specific genes

JZM Chan, AD Millard, NH Mann… - Frontiers in microbiology, 2014 - frontiersin.org
Two bacteriophages, RPP1 and RLP1, infecting members of the marine Roseobacter clade
were isolated from seawater. Their linear genomes are 74.7 and 74.6 kb and encode 91 and …

Functional domains of Acinetobacter bacteriophage tail fibers

DL Peters, F Gaudreault, W Chen - Frontiers in Microbiology, 2024 - frontiersin.org
A rapid increase in antimicrobial resistant bacterial infections around the world is causing a
global health crisis. The Gram-negative bacterium Acinetobacter baumannii is categorized …

The characteristics and genome analysis of vB_ApiP_XC38, a novel phage infecting Acinetobacter pittii

M Cheng, M Luo, H Xi, Y Zhao, S Le, LK Chen, D Tan… - Virus Genes, 2020 - Springer
Acinetobacter pittii is an important pathogen causing nosocomial infection worldwide. In this
study, a multidrug-resistant A. pittii ABC38 was used as host bacterium to isolate the lytic …

Bacteriophage discovery and genomics

GF Hatfull - Bacteriophages: Biology, Technology, Therapy, 2021 - Springer
Bacteriophages have offered opportunities for promoting student education for many years.
The advancement of high throughput DNA sequencing technologies, however, has now …

Genomic Analysis of Two Novel Bacteriophages Infecting Acinetobacter beijerinckii and halotolerans Species

M Gomes, R Domingues, D Turner, H Oliveira - Viruses, 2023 - mdpi.com
Bacteriophages are the most diverse genetic entities on Earth. In this study, two novel
bacteriophages, nACB1 (Podoviridae morphotype) and nACB2 (Myoviridae morphotype) …