Homocysteine and age-associated disorders

EA Ostrakhovitch, S Tabibzadeh - Ageing research reviews, 2019 - Elsevier
There are numerous theories of aging, a process which still seems inevitable. Aging leads to
cancer and multi-systemic disorders as well as chronic diseases. Decline in age-associated …

Causes, consequences and public health implications of low B-vitamin status in ageing

K Porter, L Hoey, CF Hughes, M Ward, H McNulty - Nutrients, 2016 - mdpi.com
The potential protective roles of folate and the metabolically related B-vitamins (vitamins
B12, B6 and riboflavin) in diseases of ageing are of increasing research interest. The most …

[HTML][HTML] Homocysteine as a predictive factor for hip fracture in older persons

RR McLean, PF Jacques, J Selhub… - … England Journal of …, 2004 - Mass Medical Soc
Background The increased prevalence of osteoporosis among people with homocystinuria
suggests that a high serum homocysteine concentration may weaken bone by interfering …

Effects of the Mediterranean diet on longevity and age-related morbid conditions

FR Pérez-López, P Chedraui, J Haya, JL Cuadros - Maturitas, 2009 - Elsevier
OBJECTIVES: To delineate the influences of the Mediterranean diet (MD) on human
mortality and age-related morbid conditions, principally the metabolic syndrome …

Vitamins and bone health: beyond calcium and vitamin D

H Ahmadieh, A Arabi - Nutrition Reviews, 2011 - academic.oup.com
Osteoporosis is a major health disorder associated with an increased risk of fracture.
Nutrition is among the modifiable factors that influence the risk of osteoporosis and fracture …

Homocysteine and Vitamin B12 Status Relate to Bone Turnover Markers, Broadband Ultrasound Attenuation, and Fractures in Healthy Elderly People

RAM Dhonukshe‐Rutten, SMF Pluijm… - Journal of Bone and …, 2005 - academic.oup.com
Hyperhomocysteinemia may contribute to the development of osteoporosis. The relationship
of Hcy and vitamin B12 with bone turnover markers, BUA, and fracture incidence was …

Homocysteine enhances bone resorption by stimulation of osteoclast formation and activity through increased intracellular ROS generation

JM Koh, YS Lee, YS Kim, DJ Kim… - Journal of Bone and …, 2006 - academic.oup.com
Hyperhomocystinemia is a modifiable risk factor for osteoporosis and fracture. Physiologic
concentrations of Hcy directly activate osteoclast formation and activity through stimulation of …

Plasma total homocysteine level and bone mineral density: the Hordaland Homocysteine Study

CG Gjesdal, SE Vollset, PM Ueland… - Archives of internal …, 2006 - jamanetwork.com
Background Plasma total homocysteine (tHcy) has been associated with hip fracture but not
directly with bone mineral density (BMD). We examined the association of hip BMD with …

Plasma Homocysteine, Folate, and Vitamin B12 and the Risk of Hip Fracture: The Hordaland Homocysteine Study

CG Gjesdal, SE Vollset, PM Ueland… - Journal of bone and …, 2007 - academic.oup.com
Homocysteine and related factors were evaluated as risk factors for subsequent hip fractures
among 4766 elderly men and women. High levels of homocysteine and low levels of folate …

Relation of homocysteine, folate, and vitamin B12 to bone mineral density of postmenopausal women

A Cagnacci, F Baldassari, G Rivolta, S Arangino… - Bone, 2003 - Elsevier
Genetic hyperhomocysteinemia is associated with skeletal abnormalities and osteoporosis.
We tested whether levels of homocysteine and critical co-enzymes of homocysteine …