Currently, cancer ranks as the second leading cause of death worldwide, and at the same
time, the burden of cancer continues to increase. The underlying molecular pathways …

Liver fibrosis is a dynamic wound-healing process associated with the deposition of
extracellular matrix produced by myofibroblasts. HSCs activation, inflammation, oxidative …

Nutraceuticals which are abundant in foods have attracted much attention due to their
bioactive activities of anti-obesity, anti-hyperlipidemia and anti-atherosclerosis …

Several studies highlighted the beneficial value of natural compounds in the prevention and
treatment of obesity. Here, we investigated the anti-obesity effects of extracts of peel and …

Aim To evaluate the effects of single PPARα or PPARγ activation, and their synergism
(combined PPARα/γ activation) upon the gut-adipose tissue axis, focusing on the …

Switching microglia from a disease exacerbating,'pro-inflammatory'state into a
neuroprotective,'anti-inflammatory'phenotype is a promising strategy for addressing multiple …

Gemcitabine (GEM) is a non-selective chemotherapeutic agent used in the treatment of
pancreatic cancer. Its antitumor efficacy is limited by a short plasma half-life and severe …

Modern lifestyle‐associated factors, such as high‐calorie intake, high‐fat diet (HFD), and
excessive artificial light, are risk factors for glucose and lipid metabolism disturbances …

Epidemiologic studies show that the levels of air pollutants and particulate matter are
positively associated with the morbidity and mortality of cardiovascular diseases. Here we …

The size of liposomal drugs has been demonstrated to strongly correlate with their
pharmacokinetics and pharmacodynamics. While the microfluidic method successfully …