This review discusses and summarizes the recent developments and advances in the use of
biodegradable materials for bone repair purposes. The choice between using degradable …

The use of bone grafts is the standard to treat skeletal fractures, or to replace and regenerate
lost bone, as demonstrated by the large number of bone graft procedures performed …

The worldwide incidence of bone disorders and conditions has trended steeply upward and
is expected to double by 2020, especially in populations where aging is coupled with …

Despite substantial attention given to the development of osteoregenerative biomaterials,
severe deficiencies remain in current products. These limitations include an inability to …

Biopolymer based hydrogels are characteristic of their biocompatibility and capability of
mimicking extracellular matrix structure to support cellular behavior. However, these …

Growth plate cartilage has limited self-repair ability, leading to poor bone bridge formation
post-injury and ultimately limb growth defects in children. The current corrective surgeries …

Bone tissue engineered 3-D constructs customized to patient-specific needs are emerging
as attractive biomimetic scaffolds to enhance bone cell and tissue growth and differentiation …

The repair and regeneration of large bone defects resulting from disease or trauma remains
a significant clinical challenge. Bioactive glass has appealing characteristics as a scaffold …

Selective laser melting (SLM) can produce complex hierarchical architectures paving the
way for highly customisable biodegradable load-bearing bone scaffolds. For the first time, an …

Critical‐sized defects in bone, whether induced by primary tumor resection, trauma, or
selective surgery have in many cases presented insurmountable challenges to the current …