Next-generation sequencing: insights to advance clinical investigations of the microbiome

CR Wensel, JL Pluznick, SL Salzberg… - The Journal of clinical …, 2022 - Am Soc Clin Investig
Next-generation sequencing (NGS) technology has advanced our understanding of the
human microbiome by allowing for the discovery and characterization of unculturable …

A systematic review of gut microbiota composition in observational studies of major depressive disorder, bipolar disorder and schizophrenia

AJ McGuinness, JA Davis, SL Dawson… - Molecular …, 2022 - nature.com
The emerging understanding of gut microbiota as 'metabolic machinery'influencing many
aspects of physiology has gained substantial attention in the field of psychiatry. This is …

ImageGP: An easy‐to‐use data visualization web server for scientific researchers

T Chen, YX Liu, L Huang - Imeta, 2022 - Wiley Online Library
Data visualization plays a crucial role in illustrating results and sharing knowledge among
researchers. Though many types of visualization tools are widely used, most of them require …

Mass spectrometry-based metabolomics in microbiome investigations

A Bauermeister, H Mannochio-Russo… - Nature Reviews …, 2022 - nature.com
Microbiotas are a malleable part of ecosystems, including the human ecosystem.
Microorganisms affect not only the chemistry of their specific niche, such as the human gut …

Fecal microbiota transplantation protects rotenone-induced Parkinson's disease mice via suppressing inflammation mediated by the lipopolysaccharide-TLR4 …

Z Zhao, J Ning, X Bao, M Shang, J Ma, G Li, D Zhang - Microbiome, 2021 - Springer
Background Parkinson's disease (PD) is a prevalent neurodegenerative disorder, displaying
not only well-known motor deficits but also gastrointestinal dysfunctions. Consistently, it has …

Microplastics change soil properties, heavy metal availability and bacterial community in a Pb-Zn-contaminated soil

X Feng, Q Wang, Y Sun, S Zhang, F Wang - Journal of Hazardous materials, 2022 - Elsevier
Microplastics (MPs) co-occur widely with diverse contaminants in soils. However, few data
are available on their impacts on soil chemical and microbial properties of heavy metal …

Randomized controlled trial for time-restricted eating in healthy volunteers without obesity

Z Xie, Y Sun, Y Ye, D Hu, H Zhang, Z He… - Nature …, 2022 - nature.com
Time-restricted feeding (TRF) improves metabolic health. Both early TRF (eTRF, food intake
restricted to the early part of the day) and mid-day TRF (mTRF, food intake restricted to the …

A metabolomics pipeline for the mechanistic interrogation of the gut microbiome

S Han, W Van Treuren, CR Fischer, BD Merrill… - Nature, 2021 - nature.com
Gut microorganisms modulate host phenotypes and are associated with numerous health
effects in humans, ranging from host responses to cancer immunotherapy to metabolic …

Health and disease markers correlate with gut microbiome composition across thousands of people

O Manor, CL Dai, SA Kornilov, B Smith… - Nature …, 2020 - nature.com
Variation in the human gut microbiome can reflect host lifestyle and behaviors and influence
disease biomarker levels in the blood. Understanding the relationships between gut …

[HTML][HTML] Proteogenomic characterization identifies clinically relevant subgroups of intrahepatic cholangiocarcinoma

L Dong, D Lu, R Chen, Y Lin, H Zhu, Z Zhang, S Cai… - Cancer cell, 2022 - cell.com
We performed proteogenomic characterization of intrahepatic cholangiocarcinoma (iCCA)
using paired tumor and adjacent liver tissues from 262 patients. Integrated proteogenomic …