Dimethyl sulfoxide is generally characterized as a solvent and oxidant rather than as a
substrate, building block, or synthon in organic chemistry. However, an abundance of …

This manuscript discloses an efficient construction of the spirocyclic oxindole-
dihydropyranone scaffold via the N-heterocyclic carbene (NHC)-catalyzed oxidative γ …

3-Hydroxy-2-oxindole derivatives, which contain a quaternary stereogenic center at the 3-
position, are a family of structurally diverse natural or nonnatural products with interesting …

Chiral N‐heterocyclic carbenes were found to be efficient catalysts for the formal [2+ 2]
cycloaddition reaction of disubstituted ketenes and isatins to give the corresponding …

A new and stereoselective synthetic approach to spirooxindole 4 H-pran-2-one derivatives
with three contiguous stereogenic centers has been developed via an NHC-catalyzed three …

An efficient and controllable protocol for the synthesis of 3-chloro-and 3, 3-dichloro-2-
oxindoles has been developed via hypervalent iodine-promoted chlorooxidation. By using …

A copper sulfate pentahydrate‐catalyzed intramolecular Friedel–Crafts reaction using an
oxocarbenium species derived from a furan ring as the alkylating agent was developed for …

The sodium iodide/hydrogen peroxide‐mediated oxidation/lactonization of indolepropionic
acids was achieved, affording the corresponding spirocyclic oxindole‐lactones in moderate …

Spirooxindole moiety is an important heterocyclic framework that is present as the core
structural unit in several biologically active synthetic and naturally occurring molecules. The …

A new dimethylsulfoxide activation method employing 1, 1-dichlorocycloheptatriene has
been developed for a mild Swern-type oxidation of a variety of alcohols. The carbonyl …