Early intervention service systems for youth mental health: integrating pluripotentiality, clinical staging, and transdiagnostic lessons from early psychosis

JL Shah, N Jones, J van Os, PD McGorry… - The Lancet …, 2022 - thelancet.com
Challenges associated with operationalising services for the at-risk mental state for
psychosis solely in that same diagnostic silo are increasingly well recognised—namely, the …

Clinical staging of psychiatric disorders: a heuristic framework for choosing earlier, safer and more effective interventions

PD McGorry, IB Hickie, AR Yung… - Australian & New …, 2006 - journals.sagepub.com
Diagnosis in psychiatry increasingly struggles to fulfil its key purposes, namely, to guide
treatment and to predict outcome. The clinical staging model, widely used in clinical …

Effect of ω-3 polyunsaturated fatty acids in young people at ultrahigh risk for psychotic disorders: the NEURAPRO randomized clinical trial

PD McGorry, B Nelson, C Markulev, HP Yuen… - JAMA …, 2017 - jamanetwork.com
Importance A promising treatment to prevent onset and improve outcomes in patients at
ultrahigh risk for psychosis is dietary supplementation with long-chain ω-3 polyunsaturated …

Prediction of psychosis in youth at high clinical risk: a multisite longitudinal study in North America

TD Cannon, K Cadenhead, B Cornblatt… - Archives of general …, 2008 - jamanetwork.com
Context Early detection and prospective evaluation of individuals who will develop
schizophrenia or other psychotic disorders are critical to efforts to isolate mechanisms …

Psychosis risk screening with the Prodromal Questionnaire—brief version (PQ-B)

RL Loewy, R Pearson, S Vinogradov, CE Bearden… - Schizophrenia …, 2011 - Elsevier
In this study, we examined the preliminary concurrent validity of a brief version of the
Prodromal Questionnaire (PQ-B), a self-report screening measure for psychosis risk …

[HTML][HTML] Early intervention in psychosis: concepts, evidence and future directions

PD McGorry, E Killackey, A Yung - World psychiatry, 2008 - ncbi.nlm.nih.gov
The rise of the early intervention paradigm in psychotic disorders represents a maturing of
the therapeutic approach in psychiatry, as it embraces practical preventive strategies which …

Individual differences in the executive control of attention, memory, and thought, and their associations with schizotypy.

MJ Kane, ME Meier, BA Smeekens… - Journal of …, 2016 - psycnet.apa.org
A large correlational study took a latent-variable approach to the generality of executive
control by testing the individual-differences structure of executive-attention capabilities and …

Declining transition rate in ultra high risk (prodromal) services: dilution or reduction of risk?

AR Yung, HP Yuen, G Berger, S Francey… - Schizophrenia …, 2007 - academic.oup.com
There is growing interest in the prodromal stage of psychotic disorders, with many services
now providing care for these “ultra high risk”(UHR) individuals. However, a reduction in the …

Preventing progression to first-episode psychosis in early initial prodromal states

A Bechdolf, M Wagner, S Ruhrmann… - The British Journal of …, 2012 - cambridge.org
BackgroundYoung people with self-experienced cognitive thought and perception deficits
(basic symptoms) may present with an early initial prodromal state (EIPS) of psychosis in …

Social cognitive functioning in prodromal psychosis: a meta-analysis

TY Lee, SB Hong, NY Shin, JS Kwon - Schizophrenia research, 2015 - Elsevier
Background There is substantial evidence regarding a social cognitive deficit in
schizophrenia, and it has been suggested to be a trait-marker of this disorder. However, a …