[HTML][HTML] From discovery to treatment: tracing the path of hepatitis E virus
A Letafati, Z Taghiabadi, M Roushanzamir… - Virology journal, 2024 - Springer
The hepatitis E virus (HEV) is a major cause of acute viral hepatitis worldwide. HEV is
classified into eight genotypes, labeled HEV-1 through HEV-8. Genotypes 1 and 2 …
classified into eight genotypes, labeled HEV-1 through HEV-8. Genotypes 1 and 2 …
[HTML][HTML] Pathogenesis and clinical features of severe hepatitis E virus infection
L Orosz, KP Sárvári, Á Dernovics… - World Journal of …, 2024 - ncbi.nlm.nih.gov
The hepatitis E virus (HEV), a member of the Hepeviridae family, is a small, non-enveloped
icosahedral virus divided into eight distinct genotypes (HEV-1 to HEV-8). Only genotypes 1 …
icosahedral virus divided into eight distinct genotypes (HEV-1 to HEV-8). Only genotypes 1 …
Hepatoprotective effect of Ginkgo biloba extract against methotrexate-induced hepatotoxicity via targeting STAT3/miRNA-21 axis
IO Sherif, NH Al-Shaalan - Drug and chemical toxicology, 2022 - Taylor & Francis
The usage of the chemotherapeutic agent methotrexate (MTX) was associated with
hepatotoxicity that minimized its clinical use. The Ginkgo biloba extract (GBE) was used …
hepatotoxicity that minimized its clinical use. The Ginkgo biloba extract (GBE) was used …
MicroRNA‐450b‐3p inhibits cell growth by targeting phosphoglycerate kinase 1 in hepatocellular carcinoma
Z Chen, W Zhuang, Z Wang, W Xiao… - Journal of Cellular …, 2019 - Wiley Online Library
Dysregulation of microRNAs frequently contributes to the occurrence and progression of
human diseases, including hepatocellular carcinoma (HCC). In this study, the role of miR …
human diseases, including hepatocellular carcinoma (HCC). In this study, the role of miR …
Specific plasma MicroRNA signatures underlying the clinical outcomes of hepatitis E virus infection
MI Costafreda, S Sauleda, M Riveiro-Barciela… - Microbiology …, 2023 - Am Soc Microbiol
The pathogenic mechanisms determining the diverse clinical outcomes of HEV infection (eg,
self-limiting versus chronic or symptomatic versus asymptomatic) are not yet understood …
self-limiting versus chronic or symptomatic versus asymptomatic) are not yet understood …
[HTML][HTML] Genome-wide association study identifies several loci for HEV seropositivity
Hepatitis E viral (HEV) infection imposes a heavy global health burden. The variability in the
prevalence of serological markers of HEV infection between different ethnic groups …
prevalence of serological markers of HEV infection between different ethnic groups …
Uncovering the roles of miR-214 in hepatitis E virus replication
Viral pathogenesis is a complex event and its regulation involve dynamic interactions with
various host factors, of which microRNAs are the key players. In the current study, we have …
various host factors, of which microRNAs are the key players. In the current study, we have …
[HTML][HTML] Specific circulating microRNAs during hepatitis E infection can serve as indicator for chronic hepatitis E
D Harms, M Choi, K Allers, B Wang, H Pietsch… - Scientific Reports, 2020 - nature.com
Hepatitis E virus (HEV) genotypes 3 and 4 (HEV-3, HEV-4) infections are an emerging
public health issue in industrialized countries. HEV-3 and− 4 are usually self-limiting but can …
public health issue in industrialized countries. HEV-3 and− 4 are usually self-limiting but can …
miR-431-5p alters the epithelial-to-mesenchymal transition markers by targeting UROC28 in hepatoma cells
Q Kong, J Han, H Deng, F Wu, S Guo… - OncoTargets and …, 2018 - Taylor & Francis
Objective MicroRNA (miR)-431 plays an essential role in various human cancer types,
particularly in the process of invasion. However, the function and mechanism of miR-431-5p …
particularly in the process of invasion. However, the function and mechanism of miR-431-5p …
[HTML][HTML] miRNA-ome plasma analysis unveils changes in blood–brain barrier integrity associated with acute liver failure in rats
K Orzeł-Gajowik, K Milewski, M Zielińska - Fluids and Barriers of the CNS, 2023 - Springer
Background Hepatic encephalopathy (HE) symptoms associated with liver insufficiency are
linked to the neurotoxic effects of ammonia and other toxic metabolites reaching the brain …
linked to the neurotoxic effects of ammonia and other toxic metabolites reaching the brain …