Diffuse pleural mesothelioma (DPM) is a highly aggressive malignant neoplasm arising from
the mesothelial cells lining the pleural surfaces. While DPM is a well-recognized disease …

Mesothelioma is a cancer typically caused by asbestos. Mechanistically, asbestos
carcinogenesis has been linked to the asbestos-induced release of HMGB1 from the …

Background More than half of mesothelioma tumours show alterations in the tumour
suppressor gene BAP1. BAP1-deficient mesothelioma is shown to be sensitive to EZH2 …

Immunotherapies have shown great promise in pleural mesothelioma (PM), yet most
patients still do not achieve significant clinical response, highlighting the importance of …

Huang et al. 1 report in the Journal of Thoracic Oncology a significant declining trend in the
incidence of diffuse malignant mesothelioma for the past decade in most industrialized …

Purpose Mesothelioma is an incurable, asbestos-related cancer with a poor prognosis.
There is scant evidence about the mental health and well-being impacts on patients and …

Background Pleural disease is common, representing 5% of the acute medical workload,
and its incidence is rising, partly due to the ageing population. Frailty is an important feature …

Purpose Mesothelioma is an incurable, asbestos related cancer with a poor prognosis. Little
is known about how patients and carers living with the condition manage their mental health …

Background Asbestos lung content is regarded as the most reliable tool for causal attribution
of malignant mesothelioma (MM) to previous asbestos exposures. However, there is a lack …

Background The identification of prognostic biomarkers is crucial for guiding treatment
strategies in mesothelioma patients. The Duchenne muscular dystrophy (DMD) gene and its …