[HTML][HTML] Acute myeloid leukemia in children: emerging paradigms in genetics and new approaches to therapy
SE Conneely, AM Stevens - Current oncology reports, 2021 - Springer
Abstract Purpose of Review Acute myeloid leukemia (AML) in children remains a
challenging disease to cure with suboptimal outcomes particularly when compared to the …
challenging disease to cure with suboptimal outcomes particularly when compared to the …
[HTML][HTML] MicroRNAs and JAK/STAT3 signaling: A new promising therapeutic axis in blood cancers
Blood disorders include a wide spectrum of blood-associated malignancies resulting from
inherited or acquired defects. The ineffectiveness of existing therapies against blood …
inherited or acquired defects. The ineffectiveness of existing therapies against blood …
CREBBP alterations are associated with a poor prognosis in de novo AML
AJ Lamble, K Hagiwara, RB Gerbing… - Blood, The Journal …, 2023 - ashpublications.org
The cyclic adenosine monophosphate response elementbinding protein (CREBBP) gene is
located on chromosome 16p13 and encodes a histone acetyltransferase having the same …
located on chromosome 16p13 and encodes a histone acetyltransferase having the same …
Characteristics and outcome of patients with acute myeloid leukaemia and t (8; 16)(p11; p13): results from an International Collaborative Study
S Kayser, RK Hills, R Langova… - British journal of …, 2021 - Wiley Online Library
In acute myeloid leukaemia (AML) t (8; 16)(p11; p13)/MYST3–CREBBP is a very rare
abnormality. Previous small series suggested poor outcome. We report on 59 patients with t …
abnormality. Previous small series suggested poor outcome. We report on 59 patients with t …
The role of MOZ/KAT6A in hematological malignancies and advances in MOZ/KAT6A inhibitors
J Su, X Wang, Y Bai, M Sun, Y Yao, Y Duan - Pharmacological Research, 2021 - Elsevier
Hematological malignancies, unlike solid tumors, are a group of malignancies caused by
abnormal differentiation of hematopoietic stem cells. Monocytic leukemia zinc finger protein …
abnormal differentiation of hematopoietic stem cells. Monocytic leukemia zinc finger protein …
Leukocyte immunoglobulin‐like receptor B1 and B4 (LILRB1 and LILRB4): Highly sensitive and specific markers of acute myeloid leukemia with monocytic …
HRO Churchill, FS Fuda, J Xu, M Deng… - Cytometry Part B …, 2021 - Wiley Online Library
Background Acute myeloid leukemia (AML) with monocytic differentiation (M‐AML) remains
a diagnostic challenge largely due to lack of sensitive and specific markers for immature …
a diagnostic challenge largely due to lack of sensitive and specific markers for immature …
[HTML][HTML] Acute myeloid leukemia with rare recurring translocations—an overview of the entities included in the international consensus classification
SD Rørvik, S Torkildsen, Ø Bruserud, THA Tvedt - Annals of Hematology, 2024 - Springer
Two different systems exist for subclassification of acute myeloid leukemia (AML); the World
Health Organization (WHO) Classification and the International Consensus Classification …
Health Organization (WHO) Classification and the International Consensus Classification …
Distinctive flow cytometric and mutational profile of acute myeloid leukemia with t (8; 16)(p11; p13) translocation
B Aqil, J Gao, M Stalling, M Sukhanova… - American journal of …, 2022 - academic.oup.com
Objectives Acute myeloid leukemia (AML) with t (8; 16)(p11; p13) abnormalities is a rare,
aggressive, and diagnostically challenging subtype that results in KAT6A-CREBBP gene …
aggressive, and diagnostically challenging subtype that results in KAT6A-CREBBP gene …
MOZ/KAT6A: a promising target for acute myeloid leukemia therapy
C Zhou, W Liu, Y Duan - Future Medicinal Chemistry, 2020 - Taylor & Francis
In recent decades, epigenetics as the description of changeable and heritable phenotypes
without a change in DNA base composition has been thought to be a major factor in our risk …
without a change in DNA base composition has been thought to be a major factor in our risk …
[HTML][HTML] Two rare cases of acute myeloid leukemia with t (8; 16)(p11. 2; p13. 3) and 1q duplication: case presentation and literature review
M Liu, Y Ren, X Wang, X Lu, M Li, YM Kim, S Li… - Molecular …, 2020 - Springer
Background Acute myeloid leukemia (AML) is a complex hematological disease
characterized by genetic and clinical heterogeneity. The identification and understanding of …
characterized by genetic and clinical heterogeneity. The identification and understanding of …