Biological factors influencing depression in later life: role of aging processes and treatment implications

SM Szymkowicz, AR Gerlach, D Homiack… - Translational …, 2023 - nature.com
Late-life depression occurring in older adults is common, recurrent, and malignant. It is
characterized by affective symptoms, but also cognitive decline, medical comorbidity, and …

Moral learning and decision-making across the lifespan

PL Lockwood, W van den Bos… - Annual Review of …, 2024 - annualreviews.org
Moral learning and decision-making are crucial throughout our lives, from infancy to old age.
Emerging evidence suggests that there are important differences in learning and deciding in …

Hippocampus and temporal pole functional connectivity is associated with age and individual differences in autobiographical memory

R Setton, L Mwilambwe-Tshilobo… - Proceedings of the …, 2022 - National Acad Sciences
Recollection of one's personal past, or autobiographical memory (AM), varies across
individuals and across the life span. This manifests in the amount of episodic content …

From exploration to exploitation: A shifting mental mode in late life development

RN Spreng, GR Turner - Trends in Cognitive Sciences, 2021 - cell.com
Changes in cognition, affect, and brain function combine to promote a shift in the nature of
mentation in older adulthood, favoring exploitation of prior knowledge over exploratory …

[HTML][HTML] Serotonergic psychedelic drugs LSD and psilocybin reduce the hierarchical differentiation of unimodal and transmodal cortex

M Girn, L Roseman, B Bernhardt, J Smallwood… - NeuroImage, 2022 - Elsevier
Lysergic acid diethylamide (LSD) and psilocybin are serotonergic psychedelic compounds
with potential in the treatment of mental health disorders. Past neuroimaging investigations …

Exploration versus exploitation decisions in the human brain: A systematic review of functional neuroimaging and neuropsychological studies.

LE Wyatt, PA Hewan, J Hogeveen, RN Spreng… - Neuropsychologia, 2024 - Elsevier
Thoughts and actions are often driven by a decision to either explore new avenues with
unknown outcomes, or to exploit known options with predictable outcomes. Yet, the neural …

Test–retest reliability and predictive utility of a macroscale principal functional connectivity gradient

AR Knodt, ML Elliott, ET Whitman, A Winn… - Human Brain …, 2023 - Wiley Online Library
Mapping individual differences in brain function has been hampered by poor reliability as
well as limited interpretability. Leveraging patterns of brain‐wide functional connectivity (FC) …

[PDF][PDF] Controversies and progress on standardization of large-scale brain network nomenclature

LQ Uddin, RF Betzel, JR Cohen… - Network …, 2023 - direct.mit.edu
Progress in scientific disciplines is accompanied by standardization of terminology. Network
neuroscience, at the level of macroscale organization of the brain, is beginning to confront …

Neurocognitive aging data release with behavioral, structural and multi-echo functional MRI measures

RN Spreng, R Setton, U Alter, BN Cassidy, B Darboh… - Scientific Data, 2022 - nature.com
Central to understanding human behavior is a comprehensive mapping of brain-behavior
relations within the context of lifespan development. Reproducible discoveries depend upon …

Gradients of brain organization: Smooth sailing from methods development to user community

J Royer, C Paquola, SL Valk, M Kirschner, SJ Hong… - Neuroinformatics, 2024 - Springer
Multimodal neuroimaging grants a powerful in vivo window into the structure and function of
the human brain. Recent methodological and conceptual advances have enabled …