The prefrontal cortex (PFC) is not only important in executive functions, but also pain
processing. The latter is dependent on its connections to other areas of the cerebral …

Migraine is a prevalent primary headache disorder and is usually considered as benign.
However, structural and functional changes in the brain of individuals with migraine have …

Background Migraine is a highly prevalent primary headache disorder. Despite a high
burden of disease, key disease mechanisms are not entirely understood. Functional …

Inconsistent findings from migraine neuroimaging studies have limited attempts to localize
migraine symptomatology. Novel brain network mapping techniques offer a new approach …

Migraine is one of the most common neurological diseases and it has a huge social and
personal impact. Although head pain is the core symptom, individuals with migraine can …

Epidemiological estimates indicate that individuals with epilepsy are more likely to
experience headaches, including migraine, than individuals without epilepsy. Headaches …

Until now, a satisfying account of the cause and purpose of migraine has remained elusive.
We explain migraine within the frameworks of allostasis (the situationally-flexible, forward …

Objective To review and discuss the literature on the role of cortical structure and function in
migraine. Discussion Structural and functional findings suggest that changes in cortical …

Migraine is a complex neurological disorder affecting approximately 12% of the population.
The pathophysiology is not yet fully understood, however the clinical features of the disease …

Resting-state functional magnetic resonance imaging (rs-fMRI) is used to interrogate the
functional connectivity and network organization amongst brain regions. Functional …