Systems biology primer: the basic methods and approaches
I Tavassoly, J Goldfarb, R Iyengar - Essays in biochemistry, 2018 - portlandpress.com
Systems biology is an integrative discipline connecting the molecular components within a
single biological scale and also among different scales (eg cells, tissues and organ systems) …
single biological scale and also among different scales (eg cells, tissues and organ systems) …
Multiscale cancer modeling
Simulating cancer behavior across multiple biological scales in space and time, ie,
multiscale cancer modeling, is increasingly being recognized as a powerful tool to refine …
multiscale cancer modeling, is increasingly being recognized as a powerful tool to refine …
Comparing individual-based approaches to modelling the self-organization of multicellular tissues
The coordinated behaviour of populations of cells plays a central role in tissue growth and
renewal. Cells react to their microenvironment by modulating processes such as movement …
renewal. Cells react to their microenvironment by modulating processes such as movement …
Simulating cancer growth with multiscale agent-based modeling
There have been many techniques developed in recent years to in silico model a variety of
cancer behaviors. Agent-based modeling is a specific discrete-based hybrid modeling …
cancer behaviors. Agent-based modeling is a specific discrete-based hybrid modeling …
Multi-scale modelling and simulation in systems biology
The aim of systems biology is to describe and understand biology at a global scale where
biological functions are recognised as a result of complex mechanisms that happen at …
biological functions are recognised as a result of complex mechanisms that happen at …
Modeling formalisms in systems biology
Abstract Systems Biology has taken advantage of computational tools and high-throughput
experimental data to model several biological processes. These include signaling, gene …
experimental data to model several biological processes. These include signaling, gene …
High performance cellular level agent-based simulation with FLAME for the GPU
Driven by the availability of experimental data and ability to simulate a biological scale
which is of immediate interest, the cellular scale is fast emerging as an ideal candidate for …
which is of immediate interest, the cellular scale is fast emerging as an ideal candidate for …
Strategies for efficient numerical implementation of hybrid multi-scale agent-based models to describe biological systems
Biologically related processes operate across multiple spatiotemporal scales. For
computational modeling methodologies to mimic this biological complexity, individual scale …
computational modeling methodologies to mimic this biological complexity, individual scale …
Multi-scale modeling of the cardiovascular system: disease development, progression, and clinical intervention
Cardiovascular diseases (CVDs) are the leading cause of death in the western world. With
the current development of clinical diagnostics to more accurately measure the extent and …
the current development of clinical diagnostics to more accurately measure the extent and …
[HTML][HTML] Systems biology of kidney diseases
Kidney diseases manifest in progressive loss of renal function, which ultimately leads to
complete kidney failure. The mechanisms underlying the origins and progression of kidney …
complete kidney failure. The mechanisms underlying the origins and progression of kidney …