Glycosylation is a ubiquitous post-translational modification responsible for a multitude of
crucial biological roles. As obligate parasites, viruses exploit host-cell machinery to …

Antibodies have been used for more than 100 years in the therapy of infectious diseases,
but a new generation of highly potent and/or broadly cross-reactive human monoclonal …

Severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS)
coronaviruses (CoVs) are zoonotic pathogens with high fatality rates and pandemic …

Summary The HIV-1-envelope (Env) trimer is covered by a glycan shield of∼ 90 N-linked
oligosaccharides, which comprises roughly half its mass and is a key component of HIV …

Detailed studies of the broadly neutralizing antibodies (bNAbs) that underlie the best
available examples of the humoral immune response to HIV are providing important …

Enveloped viruses encompass some of the most common human pathogens causing
infections of different severity, ranging from no or very few symptoms to lethal disease as …

Influenza A virus is one of the most important zoonotic pathogens that can cause severe
symptoms and has the potential to cause high number of deaths and great economic loss …

The threat of a major coronavirus pandemic urges the development of strategies to combat
these pathogens. Human coronavirus NL63 (HCoV-NL63) is an α-coronavirus that can …

Since the discovery in 1796 by Edward Jenner of vaccinia virus as a way to prevent and
finally eradicate smallpox, the concept of using a virus to fight another virus has evolved into …

The Lassa virus is endemic in parts of West Africa, and it causes hemorrhagic fever with high
mortality. The development of a recombinant protein vaccine has been hampered by the …